Old drug offers new hope against rare, deadly childhood disease​

Washington University School of Medicine in St. Louis is playing a leading role in one of the National Institutes of Health’s first clinical trials to improve treatments for rare and neglected diseases. In this case, the disease is Niemann-Pick Type C, a disorder that causes excess cholesterol to accumulate in the brain, liver and spleen. It affects about 500 children worldwide, leads to neurodegeneration, and usually causes death in the first two decades of life.

Cholesterol buildup links atherosclerosis and macular degeneration

A new study raises the intriguing possibility that drugs prescribed to lower cholesterol may be effective against macular degeneration, a blinding eye disease. Researchers at Washington University School of Medicine in St. Louis have found that age-related macular degeneration shares a common link with atherosclerosis. Both problems have the same underlying defect: the inability to remove a buildup of fat and cholesterol.

Ground broken for Shriners Hospital on Medical Campus​

A groundbreaking for a new, $50 million Shriners Hospitals for Children-St. Louis recently was held on the Washington University Medical Center campus. The planned hospital, at the corner of Clayton Road and Newstead Avenue, will replace the Shriners Hospital in Frontenac. Shown is a rendering of what the building will look like from Interstate 64/Highway 40.
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