Fat signals control energy levels in the brain

Fat signals control energy levels in the brain

An enzyme secreted by the body’s fat tissue controls energy levels in the brain, according to new research led by Shin-ichiro Imai, MD, PhD, of the School of Medicine. The findings, in mice, underscore a role for the body’s fat tissue in controlling the brain’s response to food scarcity, and suggest there is an optimal amount of body fat for maximizing health and longevity.

Marathon winner Andrea Karl says running makes her a better scientist​​

Washington University in St. Louis graduate student Andrea Karl found herself thrust into the national spotlight this month at the St. Louis GO! Marathon when an imposter at the finish line denied Karl her first-place accolades. She got to recreate the finish at Busch Stadium. Karl is working towards a PhD in molecular genetics and genomics in the Division of Biology & Biomedical Sciences (DBBS) at the School of Medicine. DBBS is in the Graduate School of Arts & Sciences.

Meyer receives grant for rotator-cuff research

Gretchen Meyer, PhD, an instructor in physical therapy and in neurology at Washington University School of Medicine in St. Louis, has received a $35,000 grant from the university’s Musculoskeletal Research Center for research titled “Promoting Rotator-cuff Muscle Regeneration With Paracrine Adipose Signaling.”

Miles to be Genentech Research Fellow

George E. Miles, MD, PhD, a clinical fellow in molecular genetic pathology, in July will become the first Genentech Research Fellow in the Department of Pathology and Immunology at Washington University School of Medicine in St. Louis.

Finding points to a cause of chronic lung disease

Scientists have long suspected that respiratory viruses play a critical role in the development of chronic lung diseases such as asthma and chronic obstructive pulmonary disease (COPD). Studying mouse and cell models of this process, researchers now have shown how immune cells dispatched to the lung to destroy a respiratory virus can fail to disperse after their job is done, setting off a chain of inflammatory events that leads to long-term lung problems.
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