School of Medicine

​​Timothy J. Ley, MD, a leukemia researcher and hematologist at the School of Medicine, has received a seven-year, $6.4 million Outstanding Investigator Award from the National Cancer Institute (NCI) of the National Institutes of Health (NIH). The funding will allow him to continue research aimed at understanding the mutations that initiate acute myeloid leukemia (AML), and how they might be targeted with new approaches.

Methadone — long used to treat pain and addiction — can be lethal if it lingers too long in the body. New research led by the School of Medicine’s Evan D. Kharasch, MD, PhD, has identified genetic subtypes in people that govern methadone clearance, findings that could help prevent some of the 5,000 methadone-related deaths that occur each year in the United States.

Craig A. Buchman, MD, a nationally recognized leader in otolaryngology and head and neck surgery, has been named head of the Department of Otolaryngology at the School of Medicine. He replaces Richard A. Chole, MD, PhD, who, after leading the department for 17 years, is stepping down to focus on research and patient care.

Studying mice with a variety of viral infections, scientists at the School of Medicine have demonstrated a way to dial up the body’s innate immune defenses while simultaneously attacking a protein that many viruses rely on to replicate. The findings reveal previously unknown weapons in the body’s antiviral immune arsenal and provide guidelines for designing drugs that could be effective against a broad range of viruses.

Richard L. Wahl, MD, the Elizabeth E. Mallinckrodt Professor and head of radiology at the School of Medicine, has been elected to the National Academy of Medicine, formerly known as the Institute of Medicine. Election to this academy is considered one of the highest honors in the field of health and medicine in the United States.

Babies born prematurely face an increased risk of neurological and psychiatric problems that may be due to weakened connections in brain networks linked to attention, communication and the processing of emotions, according to new School of Medicine research led by Cynthia Rogers, MD. 

Ann M. Gronowski, PhD, a professor of pathology and immunology and of obstetrics and gynecology at Washington University School of Medicine in St. Louis, presented a poster on the Women and Infants Health Specimen Consortium at this year’s American Association for Clinical Chemistry meeting.

The way our brains are wired may reveal a lot about us, according to new research co-authored by scientists at Washington University in St. Louis. For example, people with “positive” behavioral traits, such as sharp memories, many years of education and robust physical endurance, have stronger neural connections between certain brain regions than people with “negative” traits, such as smoking, aggressive behavior and a family history of alcohol abuse.

Following patients from childhood into young adulthood, a study led by Robert Strunk, MD, at Washington University School of Medicine in St. Louis shows the progression toward worse lung function in those who become obese as they grow into young adulthood.

Jonathan M. Green, MD, associate dean for human studies and executive chair of the Institutional Review Board (IRB) at Washington University, has been appointed to the Secretary’s Advisory Committee on Human Research Protections (SACHRP) within the U.S. Department of Health & Human Services. He will serve a three-year term.