Neurogenetics for all

Neurogenetics for all

Sophisticated techniques for testing hypotheses about the brain by activating and silencing genes are currently available for only a handful of model organisms. Scientists at Washington University in St. Louis are working on a simplified toolkit that will allow scientists who study animal behavior to manipulate the genomes of many other animals with the hope of accelerating progress in our understanding of the brain.
A sodium surprise

A sodium surprise

Irregular heartbeat — or arrhythmia — can have sudden and often fatal consequences. A biomedical engineering team at Washington University in St. Louis examining molecular behavior in cardiac tissue recently made a surprising discovery that could someday impact treatment of the life-threatening condition.
Unexpected innovation

Unexpected innovation

Mike Keymer, BS ’98, founded Topspin Labs, which works at the cutting edge of data and technology. Keymer, through Topspin, partners with ­organizations to find other applications for their technology and create a startup around that new use.
Engineers examine chemo-mechanics of heart defect

Engineers examine chemo-mechanics of heart defect

Elastin and collagen serve as the body’s building blocks. Any genetic mutation short-circuiting their function can have a devastating, and often lethal, health impact. For the first time, new research led by engineers at Washington University in St. Louis takes a closer look at both genetic and mechanical attributes, to better understand a disorder that affects how elastin and collagen function.
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