The large globules in the liver cells on the left are characteristic of alpha-1-antitrypsin deficiency. The image on the right shows normal liver cells.Research performed at the School of Medicine sheds light on the mechanisms that contribute to liver disease in alpha-1-AT deficiency patients. People with alpha-1-deficiency have a genetic mutation that can lead to emphysema at an early age and to liver damage. Using an experimental mouse model of the disorder, the researchers investigated the effects of a non-steroidal anti-inflammatory drug (NSAID) on liver injury.
The Gateway Older Women’s League rewards Annelise Mertz, professor emerita in the Performing Arts Department in Arts & Sciences, for decades of championing the arts.
Kenneth F. Kelton, Ph.D., professor of physics in Arts & Sciences, has been named the first Arthur Holly Compton Professor in Arts & Sciences. John F. McDonnell, vice chairman of the Board of Trustees and retired chairman of the board of McDonnell Douglas Corp., with JSM Charitable Trust, endowed the new professorship.
Robert W. Sussman, Ph.D., professor of anthropology in Arts & Sciences, has been awarded the 2006 W.W. Howells Book Prize from the American Anthropological Association for best book in biological anthropology written for a wide audience.
Cynthia White has been selected to receive The National Council of University Research Administrators 2006 Distinguished Service Award. The award is way to recognize members of NCURA who have made sustained and distinctive contributions to the organization.
School of Medicine researchers found that a malaria drug eased many symptoms of metabolic syndrome in mice. Study findings were published in the November issue of Cell Metabolism, and senior author Clay F. Semenkovich, M.D., professor of medicine and of cell biology and physiology, says funding for a clinical trial has been received.
Results from School of Medicine research suggest that a drug could save millions in health-care costs by preventing immune attacks following kidney transplants.
Photo by Tim ParkerThe Corpus Delicti: Just Desserts play analyzes the ethics of dissection using a life-sized cadaver from gelatin with fruits and vegetables for organs.