Cells talk more in areas Alzheimer’s hits first, boosting plaque component
Higher levels of cellular chatter boosts levels of amyloid beta in the brain regions that Alzheimer’s hits first, researchers at Washington University School of Medicine in St. Louis report. Amyloid beta is the main ingredient of the plaque lesions that are a hallmark of Alzheimer’s. The finding may help explain why areas that are most active when the brain rests are often among the first to develop these plaques, according to the researchers.
Sam Fox School of Design & Visual Arts honor distinguished alumni
The Sam Fox School of Design & Visual Arts honored eight outstanding architecture and art alumni at its fourth annual Awards for Distinction dinner April 28 at the Coronado Ballroom in St. Louis. The awards recognized graduates who have demonstrated creativity, innovation, leadership and vision through their contributions to the practices of art, architecture and design, as well as to WUSTL and the Sam Fox School.
Notables
Corey Deeken, PhD, instructor in surgery, has received a one-year, $99,995 2011 Research Grant from the Musculoskeletal Transplant Foundation for research titled “Enzymatic Degradation of Biological Tissue-Based Scaffold Materials and the Effect on Tensile Strength Over Time.” … David Fike, PhD, assistant professor of earth and planetary sciences in Arts & Sciences, has received a […]
More steps toward sustainability
To kick off a new Styrofoam recycling program at the School of Medicine this month, members of about 15 labs in the Department of Molecular Microbiology loaded one-year’s worth of Styrofoam into a 52-foot 18-wheeler truck April 28. Employees spent one hour loading the Styrofoam into the truck, which was filled about halfway.
Jump in communication skills led to species explosion among electric fishes
The Mormyridae, a family of African fishes that communicate by means of weak electic discharges, has more than 200 species. Given its diversity a Washington University in St. Louis biologist wondered whether changes in electric communication might have influenced rates of speciation. His work showed that the fishes evolved a complex signal-processing brain before a burst of speciation, that signal variation was higher among fishes with that brain, and that these fishes could distinguish among subtly different discharges, whereas others could not.Together it adds up to a strong case for brain evolution triggering increased diversification.
WUSTL partnership with area middle school reaping benefits
As the Brittany Woods-WUSTL partnership develops, programs that address students’ values, motivation, and attitudes are joining those that focus on academic subjects. Schools that combine academics with programs that support social development and healthy families are called community schools.
Winning the Green Cup
Members of the Sigma Chi fraternity accept a $500 prize for winning the Greek division of the Green Cup. The Green Cup compeititon lasted from March 28-April 22 and allowed residential colleges and fraternities to earn points for each percentage-point drop in per-person energy use over the competition.
Inverting a standard experiment sometimes produces different results
The standard experimental setup for measuring the cellular uptake of nanoparticles is to place cells in a well on a culture plate and cover them with culture medium containing nanoparticles. The assumption underlying these experiments is that the particles remain well-dispersed. But when a Washington University scientist turned cell cultures upside down, he discovered that this assumption doesn’t always hold. Some experiments preparing for the clinical use of nanoparticles may therefore need to be redone.
Anyone for tennis?
Tennis legend and women’s rights activist Billie Jean King (center) chats with WUSTL women’s tennis team members April 21 in the Knight Center. King was on campus, along with Ilana Kloss, former professional tennis player and CEO of World Team Tennis, to address students in the Olin Business School course on sports management.
Two Washington University in St. Louis geologists comment on the Japanese earthquake
In the weeks following the earthquake, two geologists at Washington University in St. Louis — Doug Wiens, PhD, professor and chair of earth and planetary sciences in Arts & Sciences, and Michael Wysession, PhD, associate professor of earth and planetary sciences — were frequently interviewed by journalists seeking to understand a catastrophe that seemed at times beyond understanding. What did the two scientists think about the quake? What was expected and what surprised them?
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