Alzheimer’s may leave some forms of memory intact

Howard Hughes Medical Institute (HHMI) researchers have made the surprising discovery that people with Alzheimer’s disease retain the capability for a specific form of memory used for rote learning of skills, even though their memories of people and events are extinguished. The scientists’ discovery suggests new strategies to improve training and rehabilitative programs that may bolster the retained cognitive function of those with Alzheimer’s disease and healthy older people.

Researchers show Io vaporizing rock gases into atmosphere

Io, satellite of Jupiter, is the most volcanically active and hottest body in the solar system.The hottest spot in the solar system is neither Mercury, Venus, nor St. Louis in the summer. Io, one of the four satellites that the Italian astronomer Galileo discovered orbiting Jupiter almost 400 years ago, takes that prize. The Voyager spacecraft discovered volcanic activity on Io over 20 years ago and subsequent observations show that Io is the most volcanically active body in the solar system. The Galileo spacecraft, named in honor of the astronomer Galileo, found volcanic hot spots with temperatures as high as 2,910 Fahrenheit (1,610 Celsius). Now computer models of volcanic eruptions on Io performed by researchers at Washington University in St. Louis show that the lavas are so hot that they are vaporizing sodium, potassium, silicon and iron and probably other gases as well into its atmosphere.

Geologists map Cartwright Country

The Ponderosa gang. The “Big Bonanza” was part of the Comstock Lode, now newly mapped.Remember the burning Ponderosa map at the beginning of the long-running TV show “Bonanza”? It’s up in flames before you can read all the place names. Now a geologist at Washington University in St. Louis has replaced that map with one of the famous ore site known as the Comstock Lode, a part of which is the “Big Bonanza.” While it’s doubtful that Hoss, Adam and Little Joe – not to mention the sages, Pa and Hop Sing – could make heads nor tails of it, the map is a valuable contribution to geology because it gives an interpretation of the flow of hot waters interacting with rock some 14 million years ago that created the ore district.

Advances in technology impact value of workers’ skills

MacDonaldIt is no secret that advances in technology can greatly impact the value of workers’ skills. Older workers often find the updating of complex technology uneconomic, while younger workers acquire and readily employ skills tailored to the newest technology. The result: the latter group’s productivity rises, diminishing the value of output produced by their older counterparts. A recently published study by Glenn MacDonald, Washington University’s John M. Olin Distinguished Professor of Economics and Strategy, is the first to model and explain the nature and severity of this effect.

Opposition to charter school movement ‘misguided,’ says expert in U.S. legal, social history

Charter schools are attended disproportionately by poor, minority students.Since their creation in the early 1990s, charter schools have come under fire from many civil rights supporters. “Traditional advocates of civil rights claim that charter schools are but another opportunity for whites to escape from the public school system and gain advantage for their children at taxpayers’ expense,” says Tomiko Brown-Nagin, associate professor of law and of history at Washington University in St. Louis. “This criticism overlooks the astounding fact, however, that most charter schools have been established in poor, minority neighborhoods and are attended disproportionately by poor, minority students — those whose schools and neighborhoods have been untouched by Brown v. Board of Education.”

No consensus on when, how, by whom — even if — Alzheimer’s patients are told of their disease

Photo courtesy of Alzheimer’s Association, St. Louis ChapterA WUSTL psychologist says there is little consensus among doctors when it comes to disclosing a dementia diagnosis to patients and their caregivers.To tell or not to tell, that is the question. Should Alzheimer’s disease patients be told of the diagnosis? If so, when, how and by whom? Brian D. Carpenter, Ph.D., an assistant professor of psychology in Arts & Sciences at Washington University in St. Louis, conducted a review of related study literature that shows there is little consensus among clinicians on the issue of disclosing a dementia diagnosis and great room for much more research. Carpenter’s review, done with research assistant Jennifer Dave, was published in the April 2004 issue of The Gerontologist. “If contemporary debate and practice are any indication, there is no consensus on these matters,” Carpenter says in the article “Disclosing a Dementia Diagnosis: A Review of Opinion and Practice, and a Proposed Research Agenda.”

Human subjects play mind games

That’s using your brain. For the first time in humans, a team headed by researchers at Washington University in St. Louis has placed an electronic grid atop patients’ brains to gather motor signals that enable patients to play a computer game using only the signals from their brains.

Holidays and special events have no proven effect on the timing of death

WUSTL researchers have found no convincing evidence that people can delay or hasten their own deaths through sheer will.Many of us know stories about terminally ill friends or relatives who were able to battle their illnesses in order to survive until a birthday or other important occasion. In much of medicine, it’s an accepted “truth” that people can hang on or give up and somehow influence the timing of their own deaths. But in reviewing every study on the subject of delaying death, Washington University behavioral medicine researchers have found that there’s no evidence to support the idea that terminally ill people can have an effect on when they die.

Natural mechanism in brain cells may resist stroke damage

In this micrograph of a neuron, green dye highlights proteins linked to nerve cell damage and death during stroke.Brain cells in danger of exciting other nearby brain cells to death may be able to close temporarily, according to new research from Washington University School of Medicine in St. Louis. Scientists simulated stroke-like conditions in cultured rat brain cells that use glutamate, an excitatory chemical messenger linked to nerve damage and death during strokes. But when they created those conditions, the researchers found that glutamate transmission was suppressed in what may be an attempt by neurons to limit the damage caused by catastrophic events such as strokes.

PET scans after therapy improve cervical cancer survival predictions

GrigsbyDoctors regularly use positron emission tomography (PET) scans to diagnose cervical cancer, taking advantage of the technique’s ability to highlight metabolic differences in cancerous tissues. But PET is rarely used for follow-up assessment of cervical cancer patients after treatment. A study in the June 1 issue of Journal of Clinical Oncology shows that post-treatment PET scans could help physicians better predict which patients are largely cancer-free as a result of their treatment and which patients may soon be likely to need additional treatment.
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