Newsroom Stories

Repair proteins (bright green areas) are inhibited from gathering at sites of DNA damage.To remain healthy, all cells must quickly mend any breaks that arise in their DNA strands. But cancer cells are particularly dependent on a process called homologous recombination to repair DNA and stay alive. Now researchers at Washington University School of Medicine in St. Louis have identified a protein with a role in homologous recombination, and the discovery could be exploited as part of a two-pronged treatment strategy to kill cancer cells by eliminating their ability to repair DNA.

WUSM researchers have developed a diagnostic tool for identifying pathological gambling disorder.More than 80 percent of the U.S. population gambles at some time in their lives. It might be the lottery, bingo or poker. Most never need treatment for problem gambling, but others lose control and lose their houses or cars and damage family relationships as a result of compulsive gambling. Little is known about why people gamble and how to predict who is likely to become a pathological gambler, but Washington University researchers have developed a diagnostic tool for identifying pathological gambling disorder, and they’re beginning to learn who is at risk.

Structure of the fatty acid receptor CD36As you stand at buffet tables during holiday parties this year, it might cheer you up to know most people don’t gain as much weight over the holidays as once was thought. Instead of five or 10 pounds, most of us actually gain only a pound or two. But it might depress you to know that weight gain happens one pound at a time, and in the long run, it may be hard to avoid — especially for some of us, because some of the taste buds in our tongues are programmed to make us crave fatty food — and fat is everywhere in our diets. French researchers recently reported that mice have a receptor in their tongues that can sense fat, and the presence of that receptor seems to drive the mice to crave fat in their diets. The research was based on work from scientists at Washington University School of Medicine in St. Louis, where investigators previously had identified a protein receptor for fat and documented its function in recognizing and using fatty food.

Mania can be confused with ADHD.Child psychiatry researchers at Washington University School of Medicine in St. Louis have identified a small group of preschoolers who appear to suffer from bipolar disorder, also known as manic-depressive illness. In findings presented this fall to the American Academy of Child and Adolescent Psychiatry, the researchers reported they had identified key symptoms that distinguish bipolar disorder from other problems in very young children. Diagnosing bipolar disorder in childhood can be difficult because the manic phase of the illness can be confused with the more common attention deficit hyperactivity disorder (ADHD). The confusion arises because mania and ADHD both involve hyperactivity, irritability and distractibility.

Photo courtesy of HerPlanet Inc.Avoid a holiday-shopping nightmare.Whether it’s a last-minute rush to the mall or a year-long obsession, the quest for the “perfect gift” has the potential to turn holiday shopping into an annual nightmare. A psychologist at Washington University in St. Louis who is an expert on helping people gain control of personal habits, such as smoking and overeating, says many of the same techniques can be used to get a grip on holiday shopping.

A four-star rating from Charity Navigator — the largest independent charity evaluator in America — is the highest score possible. For the fifth consecutive year, Washington University has received a four-star rating, based on an evaluation of two broad areas of financial health.

The Department of Psychiatry at the School of Medicine is hosting a program on strategies to help patients with treatment resistant depression.

Two teams of entrepreneurs have won Washington University’s 2005 Olin Cup. Somark Innovations, Inc. and iMobile Access Technologies, or iMAT, will receive a total of $70,000 in seed funding for their enterprises. An additional $5,000 grant for student projects will be split between two winners: HomeWUrk and Suzanne Shenkman Designs. The awards were announced Dec. 1 at a ceremony featuring Robert J. Skandalaris, founder and chairman of Noble International.

Awards received by Victoria Fraser, Jay Piccirillo and Bradley Evanoff will help the division take a major step forward in educating & training clinical investigators.

He died Nov. 10 of prostate cancer; the survey contributed to a ban on testing nuclear weapons in the atmosphere.