Newsroom Stories

Eliminating a molecular signal can help protect a neuron (show here) from destructive immune system cells.It may sound like a case of blame the victim, but researchers at Washington University School of Medicine in St. Louis have shown that cells in the central nervous system can sometimes send out signals that invite hostile immune system attacks. In mice the researchers studied, this invitation resulted in damage to the protective covering of nerves, causing a disease resembling multiple sclerosis. The researchers found that they could prevent destructive immune cells from entering nervous system tissue by eliminating a molecular switch that sends “come here” messages to immune cells.

Charles Huddleston performs a pediatric lung transplant.A team of researchers at Washington University School of Medicine in St. Louis has found that using lobes of lungs from living donors improves the chances of short-term survival for children who require a second lung transplant. Researchers compared the outcomes of lung retransplants in 39 children, including 13 patients who had lung retransplants using lobes from living donors and 26 who received lung retransplants using whole lungs from deceased donors. Living-donor lung retransplantation involves removing a lower lobe, or about one-third of a lung, from each of two healthy adult donors and then transplanting the lobes as replacement lungs into a child.

Histamine in the small intestine (shown in green) responding to the bacterium *Yersinia enterocolitica*Mice infected with a bacterium related to the plague sharply increase production of an enzyme that makes the inflammatory hormone histamine, researchers at Washington University School of Medicine in St. Louis have found. The increased production, which occurs in the intestine, appears to be an important part of the mouse’s successful efforts to control the infection.

Red zones in this brain map suggest frontal parts of the brain are particularly sensitive to erotic content.A new study suggests the brain is quickly turned on and “tuned in” when a person views erotic images. Researchers at Washington University School of Medicine in St. Louis measured brainwave activity in women as they viewed a series of slides that contained various scenes from water skiers to snarling dogs to partially-clad couples in sensual poses. When study volunteers viewed erotic pictures, their brains produced electrical responses that were stronger than those elicited by other material, no matter how pleasant or disturbing the other material may have been. This difference in brainwave response emerged very quickly, suggesting that different neural circuits may be involved in the processing of erotic images.

Eliminating a molecular signal can help protect a neuron (show here) from destructive immune system cells.It may sound like a case of blame the victim, but researchers at the School of Medicine have shown that cells in the central nervous system can sometimes send out signals that invite hostile immune system attacks. In mice the researchers studied, this invitation resulted in damage to the protective covering of nerves, causing a disease resembling multiple sclerosis. The researchers found that they could prevent destructive immune cells from entering nervous system tissue by eliminating a molecular switch that sends “come here” messages to immune cells.

Susan Dutcher, Ph.D., professor of genetics and of cell biology and physiology, has been named interim head of the James S. McDonnell Department of Genetics at the School of Medicine effective July 1.

Low quality threatens the high end.What company wouldn’t attribute its profits to the quality product it produces? The answer might be: the company that competes on price. According to research from Washington University in St. Louis, producers of lower quality products actually have better prospects for gaining market share and improving their bottom line. The findings indicate the Chinese manufacturers could easily gain an edge over American producers. More…

James RichardsThe Gateway Festival Orchestra will begin its 43rd season of free summer concerts with “Midwest Musical Masters,” highlighting composers and young artists from Missouri and Illinois, at 7:30 p.m. Sunday, July 9, in Washington University’s Brookings Quadrangle. The orchestra is conducted by James Richards, professor of orchestral studies at the University of Missouri-St. Louis. Subsequent concerts take place at 7:30 p.m. Sunday, July 16 and 23 in Brookings Quadrangle. The season concludes Sunday, July 30, in Graham Chapel.

It’s not just social security and health-care that could be adversely affected when the baby boomers leave the workforce; the stock market could go into shock as well. According to research at the Olin School of Business at Washington University in St. Louis, when people retire, they tend not invest as much they did in their younger years. With the boomer generation starting to pull out of the workforce, Wall Street is bound to feel the blow. More…

Photo by Mary ButkusPreparing for kindergarten.You know what they say — everything you really need to know in life, you learn in kindergarten. Well, if that’s the case, preschoolers should be well prepared for this momentous year in their lives. But for so many little ones, kindergarten just looks — and sounds — like a big, scary place. A preschool educator at Washington University in St. Louis says it needn’t be and that with a little preparation this summer, your preschool child should be more than ready for that first big day of kindergarten in the fall. More…