e-Records launched

This issue inaugurates twice-weekly electronic distribution of the Record.

Rice domestiction confiirmed genetically

Photo courtesy USDASchaal rice one.Biologists from Washington University in St. Louis and their collaborators from Taiwan have examined the DNA sequence family tree of rice varieties and have determined that the crop was domesticated independently at least twice in various Asian locales. Jason Londo, Washington University in Arts & Sciences biology doctoral candidate, and his adviser, Barbara A. Schaal, Ph.D., Washington University Spencer T. Olin Professor of Biology in Arts & Sciences, ran genetic tests of more than 300 types of rice, including both wild and domesticated, and found genetic markers that reveal the two major rice types grown today were first grown by humans in India and Myanmar and Thailand (Oryza sativa indica) and in areas in southern China (Oryza sativa japonica). More…

Washington University, China’s ShanDong University will collaborate on Moon data

Photo courtesy NASAAmid a bevy of international space exploration missions to the Moon, the Washington University Department of Earth and Planetary Sciences in Arts & Sciences and ShanDong University at WeiHai (SDU at WH) in Mainland China have agreed to cooperate on scientific research and joint training of students in the two institutions. The agreement comes less than a year away from the planned launch of Chang’E-1, the Chinese lunar probe project, in April, 2007. The goals of China’s Chang’E-1 project are first to place a satellite into orbit around the Moon in 2007; then to land an unmanned vehicle on the Moon by 2010; and to collect samples of lunar soil with an unmanned vehicle by 2020. The spacecraft carries five instruments to image and measure different features of the Moon. Within two years, three additional missions from the United States, India and Japan will generate a furious flurry of data that will keep space scientists enthralled for the better part of the next decade. The Japanese Selene mission is scheduled to launch in the summer of 2007, the Indian Chandrayaan-1 in late 2007 or early 2008, and the United States’ Lunar Reconnaissance Orbiter for October 2008. More…

Restating earnings hurts the company itself, and its peers

When one company restates earnings, best to see what its peers are up to.No company wants to issue an accounting restatement; it’s a guaranteed way for the share price to drop 10 percent, on average. Investors, analysts and journalists alike view restatements as an indication of a problem within the company. As it turns out, restatements indicate that there is value in looking at its industry peer firms. More…

Neighborhoods key to rebuilding New Orleans, master planner says

Jessica Garz/Kelly ManningNew Orleans’ Central City, post-KatrinaThe French Quarter, the Garden District, the Treme, the Lower Ninth Ward. Perhaps more than any other American city, New Orleans is a collection of individual neighborhoods — 72 in all — each with its own history and culture. In many ways, these neighborhoods represent both the key and the key challenge to rebuilding the city, says John Hoal, Ph.D., associate professor of architecture in the Sam Fox School of Design & Visual Arts at Washington University in St. Louis. Last week, Hoal’s firm, H3 Studio Inc., was one of five selected to lead the Unified New Orleans Plan, which will coordinate rebuilding in the city’s 13 planning districts. More…

Pathway toward gene silencing described in plants

Olga Pontes is Going FISHin’.Biologists at Washington University in St. Louis have made an important breakthrough in understanding a pathway plant cells take to silence unwanted or extra genes using short bits of RNA. Basically, they have made it possible to see where, and how, the events in the pathway unfold within the cell, and seeing is believing, as the old saying goes. Craig Pikaard, Ph.D., Washington University professor of biology in Arts & Sciences and his collaborators have described the roles that eight proteins in Arabidopsis plants play in a pathway that brings about DNA methylation, an epigenetic function that involves a chemical modification of cytosine, one of the four chemical subunits of DNA. More…

It’s the wave of the future: The economy thrives, but the employment rate doesn’t

Recovering from a recession doesn’t include the entire economy.The “jobless recovery” that befuddled observers after the recession in the early 2000s was no fluke. It’s actually a pattern that we can expect to continue thanks to technology’s uneven impact across sectors of the economy. What’s more, this new trend in business cycles is as important in making policy decisions as it is in ensuring the stability of the country’s economy. More…

Reconstructive surgeon aims for rejection-free limb transplantation

Image courtesy of Jewish Hospital; Kleinert, Kutz and Associates Hand Care Center; and University of LouisvilleLimb transplantation involves several kinds of tissue.Years ago, the idea of attaching a donor limb onto a patient’s body would have been the stuff of science fiction. But to date about two-dozen people around the world have received hand transplants. Thomas Tung, M.D., conducts research within this relatively unorthodox realm of surgery, investigating the use of therapy that could potentially allow the body to accept donor tissue without the use of immunosuppressive medication.

Drug can quickly mobilize an army of cells to repair injury

Red areas of the circled leg in the right image show increased blood flow due to angiogenic cells.To speed healing at sites of injury – such as heart muscle after a heart attack or brain tissue after a stroke – doctors would like to be able to hasten the formation of new blood vessels. One promising approach is to “mobilize” patients’ blood vessel-forming cells, called angiogenic cells, so these cells can reach the injured area. Recently, researchers at Washington University School of Medicine in St. Louis demonstrated that a drug called AMD3100 can mobilize angiogenic cells from bone marrow of human patients in a matter of hours.
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