Seven-point system gauges seriousness of heart failure in elderly

A simple points system may soon help guide treatment of elderly heart failure patients. Researchers at the School of Medicine found that by counting how many of seven easy-to-obtain health factors a patient has, physicians can estimate the patient’s risk of dying.

November 2006 Radio Service

Listed below are this month’s featured news stories. • Breaking down Alzheimer’s (week of Nov. 1) • Preventing transplant rejection (week of Nov. 8) • Predicting glaucoma (week of Nov. 15) • No-incision stomach stapling (week of Nov. 22) • Organ donor health (week of Nov. 29)

NSAID increases liver damage in mice carrying mutant human gene

The large globules in the liver cells on the left are characteristic of alpha-1-antitrypsin deficiency. The image on the right shows normal liver cells.Research performed at the School of Medicine sheds light on the mechanisms that contribute to liver disease in alpha-1-AT deficiency patients. People with alpha-1-deficiency have a genetic mutation that can lead to emphysema at an early age and to liver damage. Using an experimental mouse model of the disorder, the researchers investigated the effects of a non-steroidal anti-inflammatory drug (NSAID) on liver injury.

Malaria drug could hold key to treating heart disease, diabetes

School of Medicine researchers found that a malaria drug eased many symptoms of metabolic syndrome in mice. Study findings were published in the November issue of Cell Metabolism, and senior author Clay F. Semenkovich, M.D., professor of medicine and of cell biology and physiology, says funding for a clinical trial has been received.

A stitch in time

Photo by Mary ButkusThe campus Knit-In brings together knitting enthusiasts from across campus and the community.

Just Desserts

Photo by Tim ParkerThe Corpus Delicti: Just Desserts play analyzes the ethics of dissection using a life-sized cadaver from gelatin with fruits and vegetables for organs.
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