Newsroom Stories

The pink color in the image on the right highlights cells producing excess mucus, a symptom of COPD. The image on the left shows normal lung tissue. Physicians say that smoking is by far the biggest cause of emphysema, but why doesn’t every smoker get the disease? If you asked WUSM physician Michael Holtzman that question, he might answer that for most cases of emphysema you need a mix of genes, viruses and cigarettes. Emphysema and the associated condition of chronic bronchitis are both disorders that contribute to chronic obstructive pulmonary disease (COPD), which is the fourth leading cause of death in the U.S.

The AIDS Clinical Trials Unit (ACTU) at theSchool of Medicine has received a $10 million grant to find new treatments for AIDS and HIV-related complications, such as dementia, neuropathy and cardiovascular disease. The seven-year grant is from the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health (NIH).

An immune system gene that flunked its first tryout as an antiviral factor has triumphed in its second, proving that it can help fight the flu, herpes and the Sindbis virus. Picking the right opponents for interferon stimulated gene 15 (ISG15) to square off against proved to be key to uncovering its potential.

Ralph Stewart*The Dead Father*Choreographer Paul D. Mosley — artistic director for the Vassar Repertory Dance Theatre at Vassar College in Poughkeepsie, NY — will return to St. Louis for the first time in a decade to perform an evening of new and old dance works.

The growth factor G-CSF caused bone tumors to increase in size in lab mice. The mouse on the left did not receive G-CSF. The mouse on the right did.In laboratory tests on mice, researchers found that a medication often used to reduce toxic side effects of chemotherapy induced bone loss and helped tumors grow in bone. So the researchers are recommending increased awareness of bone health during cancer treatments. The medication studied is a growth factor commonly used to help cancer patients recover healthy blood counts after chemotherapy, which can destroy white blood cells.

Feinknopf PhotographyLam Partners Inc.Lighting designer Paul A. Zaferiou will launch the Sam Fox School of Design & Visual Arts’ spring Architecture Lecture Series Jan. 22. Zaferiou, a 1975 alumnus of Washington University, is president and principal of Lam Partners Inc., a lighting consulting firm whose credits include the Guggenheim Museum in Bilbao, Spain, and The Getty Villa in Malibu, CA, among many others. The lecture series will continue Jan. 29 with Winy Maas, a principal of MVRDV, the Office of Architecture and Urbanism, in Rotterdam.

David Kilper/WUSTL Photo ServicesKaylin Boosalis as Alma and Lee Osorio as OskarIn 1973, while a doctoral student at Indiana University, Henry I. Schvey befriended the eminent Austrian expressionist painter Oskar Kokoschka (1886-1980). Now chair of Washington University’s Performing Arts Department in Arts & Sciences, Schvey has written Kokoschka: A Love Story, an original drama about the artist’s torrid affair with Alma Mahler (1879-1964), the beautiful widow of composer Gustav Mahler (1860-1911).

By all expectations, it shouldn’t have worked as well as it did. A combination of bone marrow transplantation and gene therapy greatly lengthened the lives of laboratory mice doomed by a rapidly progressing, fatal neurodegenerative disorder also found in people. The School of Medicine researchers who made the discovery set out with low hopes for the combination therapy because on its own, each treatment was only modestly effective for the sick mice.

Rafia ZafarRafia Zafar, Ph.D., professor of English, of African & African American studies and of American culture studies, all in Arts & Sciences at Washington University in St. Louis, has been awarded a Fulbright Scholar grant to lecture abroad during the 2007 spring semester. She has been awarded the distinguished Walt Whitman Chair, which includes teaching an advanced undergraduate course and a graduate seminar at Utrecht University in the Netherlands.

In remembrance of Dr. Martin Luther King Jr., the Society of Black Student Social Workers (SBSSW) at the George Warren Brown School of Social Work will host “Financial Freedom Seminar: Achieving Economic Independence Through Education,” Jan. 20 from 8:30 a.m.- 3 p.m. in Brown Hall. This free event is designed for members of the St. Louis community interested in building wealth, maintaining good credit, purchasing a home or starting a business. The deadline to register for this event is Jan. 15. “SBSSW’s goal is to present the King Holiday, not as a tradition or a history lesson, but as a call to action- to fight for economic and social justice,” says Charletra Hurt, SBSSW co-chair and first-year student at the School of Social Work.