Newsroom Stories

The schematic in the center shows how a drug molecule (in the circle) prevents UTIs by stopping pili formation.A different approach to treating urinary tract infections (UTIs) could defeat the bacteria that cause the infections without directly killing them, a strategy that could help slow the growth of antibiotic-resistant infections. Instead of trying to wipe out bacteria, researchers at the School of Medicine have been working to create pharmaceuticals that essentially “defang” the bacteria by preventing them from assembling pili, microscopic hairs that enable the bacteria to invade host cells and defend themselves against the host’s immune system.

Right now there’s no rapid way to diagnose sepsis, a fast-moving blood infection that is a leading cause of death in hospital intensive care units. Doctors who suspect sepsis typically rush to prescribe powerful antibiotics, but this can lead to the inappropriate treatment of patients with uncontrollable inflammation without an underlying infection. New research at the School of Medicine suggests that doctors one day could quickly distinguish sepsis from widespread non-infectious inflammation based on genetic profiles of patients’ blood.

As part of Washington University’s celebration of the Danforth Campus dedication, and to underscore the important role of higher education in society, a lecture series will debut on October 3 with succeeding events on October 16 and November 13 – all being held in Graham Chapel at 4 p.m. Titled “A Higher Sense of Purpose,” its speakers will cover some of the more cogent topics being discussed today, with the goal of generating new ideas and creating a dialogue to move the conversations forward. All three programs are free and open to the public.

The schematic in the center shows how a drug molecule (in the circle) prevents UTIs by stopping pili formation.A different approach to treating urinary tract infections (UTIs) could defeat the bacteria that cause the infections without directly killing them, a strategy that could help slow the growth of antibiotic-resistant infections. Instead of trying to wipe out bacteria, researchers at Washington University School of Medicine in St. Louis have been working to create pharmaceuticals that essentially “defang” the bacteria by preventing them from assembling pili, microscopic hairs that enable the bacteria to invade host cells and defend themselves against the host’s immune system.

Right now there’s no rapid way to diagnose sepsis, a fast-moving blood infection that is a leading cause of death in hospital intensive care units. Doctors who suspect sepsis typically rush to prescribe powerful antibiotics, but this can lead to the inappropriate treatment of patients with uncontrollable inflammation without an underlying infection. New research at Washington University School of Medicine in St. Louis suggests that doctors one day could quickly distinguish sepsis from widespread non-infectious inflammation based on genetic profiles of patients’ blood.

The surge of baby boomers now entering their 60s means more drivers on the road who may be impaired by dementia or other cognitive impairments linked to aging. Researchers at the Alzheimer’s Disease Research Center (ADRC) of Washington University School of Medicine in St. Louis and elsewhere have developed a three-hour workshop that trains health care providers to identify potentially unsafe drivers with dementia and to encourage appropriate retirement from driving.

David Murray demonstrates defibrillation techniques to a group of students in the Clinical Simulation Center.The Institute of Medicine estimates that medical errors are the eighth leading cause of death in the United States, and poor communication can be a major source of those errors. Now the Clinical Simulation Center at Washington University School of Medicine and Barnes-Jewish Hospital in St. Louis hopes to improve patient safety by using clinical simulators to find the source of miscommunications during medical treatments.

VIDEO AVAILABLE: Stardust, the NASA spacecraft mission, was given that name in hopes that the seven-year journey to capture comet samples would bring back to Earth, well, stardust. In an article coming out in the Dec. 15, 2006, issue of the journal Science, researchers at Washington University in St. Louis are the first to report that a sample they received from the mission actually does contain stardust — particles that are older than the sun.

Hundreds of technology-transfer offices have popped up on university campuses over the past 20 years to enable universities to facilitate the commercialization of innovations and discoveries pioneered by their professors. Licensing patents for the inventions is a commercial opportunity for universities, which hope to make money selling the intellectual property and to see faculty research make a tangible impact in the marketplace. While all the inventions might be equally genius, they aren’t all valued equally. The question for technology-transfer offices is: What will sell? A professor at the Olin School of Business found that the ease of selling intellectual property doesn’t necessarily depend on whether the innovation has received patent protection. More…

When good fortune smiles on a company, the stock market responds by valuing the firm more favorably. It’s well known that good news for one firm means other companies in the same industry will be affected as well. But a business professor at Washington University in St. Louis says we can also anticipate a predictable connection between news announcements of a company and its suppliers or customers.