Scientists search DNA for reasons why some women give birth prematurely
One in eight babies is born prematurely.Nearly one in every eight U.S. babies is born too early — three weeks or more before the estimated due date. Such premature births are the leading cause of newborn deaths and put babies at risk for chronic lung disease and other serious health problems. While some causes of prematurity are known, more than half of women who deliver early have no known risks. In an innovative approach, WUSM researchers Louis Muglia and Justin Fay are searching human DNA for clues to help explain why some women deliver early.
Nanostructures show potential to aid in the diagnosis and treatment of pediatric brain cancer
The magnified nanoparticles shown here are actually about 1,000 times smaller than the width of a human hair.Chemistry meets biology in this innovative research program. Using synthetic particles invisible to the naked eye, researchers hope to better diagnose and treat childhood brain cancer, the third most common cancer of children. The particles are called nanostructures or nanoparticles because they are measured in nanometers, an almost unimaginably small unit, a billion times shorter than a yardstick.
Sugar molecules may provide unique, new approach to treating deadly disorder
Nearly 40 percent of babies with a condition known as Simpson Golabi Behmel syndrome will die soon after birth, likely because of heart problems related to the disorder, which causes them to grow too quickly. Researchers funded by the Children’s Discovery Institute are pursuing a unique new approach to treating this disorder: they’re hoping to use long chains of sugar molecules to coax troublemaking cells back to good behavior.
Rwandan hero to give final spring talk for Assembly Series
Rwandan hero Paul Rusesabagina will speak on his experiences, his ongoing support of Rwanda, the genocide in Darfur, and current issues involving international humanitarian aid, for the final Assembly Series program at 11 a.m.. It is free and open to the public.
Breast cancer patients’ treatment response may help reveal cancer genes
Courtesy of the National Cancer InstituteBreast cancer cells stained brown using an antibody that recognizes malignant cellsClinical studies are proving that the genetic profile of a tumor can greatly influence its response to anticancer treatments. WUSM physician Matthew Ellis is conducting research that aims to use the genetic profile of breast tumors to guide breast cancer therapy and ultimately to find new drugs for treating the disease.
Dead Sea cave archaeology is focus of Richard Freund lecture, April 20
Richard Freund, director of the Maurice Greenberg Center for Judaic Studies at the University of Hartford, will discuss “Temple Treasures in the Dead Sea Caves: New Insights from Archaeology” at 11 a.m. April 20 in Room 301, Lab Sciences Building, Danforth Campus.
Crow observatory to be featured on KETC’s ‘Living St. Louis’
“Living St. Louis,” a show on KETC (Channel 9) that showcases the colorful culture of our region, will include a segment on Washington University’s Crow observatory tonight at 7 p.m. The segment will also air at 4:30 p.m. on Sunday, April 15, and by Wednesday, April 11, it will be streamed on KETC’s Web site at www.ketc.org.
Prenatal smoking increases ADHD risk in some children
Smoking while pregnant combined with genetic factors greatly increases the risk of severe ADHD.Past research has suggested that both genes and prenatal insults — such as exposure to alcohol and nicotine — can increase the risk of attention-deficit/hyperactivity disorder (ADHD). But the identified increases in risk have been very modest. Now, a team of Washington University scientists has found that when those factors are studied together, risk of a severe type of ADHD greatly increases.
Metabolic syndrome as common in HIV-infected people as in general population
New HIV therapies have contributed to a decrease in AIDS deaths, but physicians suspected the more potent medications led to symptoms characteristic of metabolic syndrome. However, now researchers at Washington University School of Medicine in St. Louis have found that the rate of metabolic syndrome in HIV-infected patients is virtually identical to that in uninfected people. Furthermore, the type or duration of HIV therapy did not affect the rate of metabolic syndrome.
Let the NO flow: discovery provides key to improving blood circulation, healing
An angiogram, or X-ray image of blood vesselsScientists have uncovered a new biomedical technique that could increase blood flow to alleviate problems associated with cardiovascular disease, diabetes and many surgical procedures. They found that blocking the action of a blood-clot-associated protein turns up the effect of a biologically produced gas that can open blood vessels and increase blood flow.
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