Discovery could increase tumors’ sensitivity to radiation therapy

Mouse embryos stained to show MOF (green) and its histone tag (red) demonstrate that MOF is essential for cell proliferation.To make tumors more sensitive to the killing power of radiation is a key aspiration for many radiation oncologists. Researchers at the School of Medicine have uncovered new information that leads them closer to that goal. In an upcoming issue of the journal Molecular and Cellular Biology, they report the first extensive study of an enzyme called MOF that helps control how DNA is packaged in cells. The researchers show that MOF is an essential factor for tumor development, and they say it may be possible to manipulate the enzyme to make tumors more sensitive to radiation therapy.

Novelist Brock Clarke to speak for Writing Program Reading Series Nov. 14

Brock ClarkeNovelist Brock Clarke, author of An Arsonist’s Guide to Writers’ Homes in New England (2007), will read from his work at 8 p.m. Wednesday, Nov. 14, for the Writing Program in Arts & Sciences. The book — Clarke’s fourth — tells the darkly comic story of Sam Pulsifer, a literary bumbler who, at the age of 18, accidentally burns down the Emily Dickinson House in Amherst, Mass.

Tom Miller, professor of radiology, 63

Tom R. Miller, M.D., Ph.D., professor of radiology and of biomedical engineering, died Wednesday, Oct. 3, 2007, at his home in Webster Groves. He was 63.

Immense new facility to house BioMed 21 research

The largest building ever constructed on the School of Medicine campus will be the home base for BioMed 21, the University’s innovative research initiative designed to speed scientific discovery and to rapidly apply breakthroughs to patient care.

Introducing new faculty members

Charly Coleman, Ph.D., Clifton R. Emery, Ph.D., Carl Minzner, J.D., John Orrock, Ph.D., Thomas Sattig, Ph.D., Vincent Sherry, Ph.D., Julie Singer, Ph.D., Ying Xie, Ph.D.
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