Researchers solve piece of large-scale gene silencing mystery
PikaardA team led by Craig Pikaard, Ph.D., WUSTL professor of biology in Arts & Sciences, has made a breakthrough in understanding the phenomenon of nucleolar dominance, the silencing of an entire parental set of ribosomal RNA genes in a hybrid plant or animal. Since the machinery involved in nucleolar dominance is some of the same machinery that can go haywire in diseases such as cancer, Pikaard and his collaborators’ research may have important implications for applied medical research. Click here for a podcast from Genetic Engineering & Biotechnology News: Interview with Craig Pikaard.
Keeping the engine humming
Photo by Robert BostonJames T. Stueber ensures the Medical Center’s systems run smoothly
Model unravels rules that govern how genes are switched on and off
Illustration by Michaela HuntFor years, scientists have struggled to decipher the genetic instruction book that details where and when the 20,000 genes in a human cell will be turned on or off. Different genes operate in each cell type at different times, and this careful orchestration is what ultimately distinguishes a brain cell from a liver or skin cell. Now, scientists at the School of Medicine report they have developed a model of gene expression in yeast that predicts with a high degree of accuracy whether a gene will be switched on or off.
With finals looming, programs help students reduce stress
With exams beginning this week, students and health educators have planned events aimed at reducing stress and giving students a break during this busy time.
Former ambassador for counternarcotics and justice reform in Afghanistan available to discuss foreign policy priorities for President Obama
“Afghanistan, Iraq and Pakistan need to be top foreign policy priorities for President Barack Obama,” says Thomas Schweich, former ambassador for counternarcotics and justice reform in Afghanistan and visiting professor of law at Washington University in St. Louis. Schweich, the Special Representative for Mexico, Central America, and the Caribbean for the United Nations Office on Drugs and Crime, is available to discuss foreign policy issues facing the next president.
Danforth Foundation donates $10 million for neurodegenerative research
The Danforth Foundation has granted the Hope Center for Neurological Disorders at the School of Medicine a $10 million endowed gift for research into a range of conditions that cause injury and impairment to the brain and central nervous system. The funds will be used to support innovative and groundbreaking new ideas for research with clear potential to improve diagnosis and treatment of patients with amyotrophic lateral sclerosis (ALS), Parkinson’s disease, stroke, Huntington’s disease, multiple sclerosis, cerebral palsy and other disorders.
Apple or pear shape is not main culprit to heart woes — it’s liver fat
Pear-shaped people who carry weight in the thighs and backside have been told for years they are at lower risk for high blood pressure and heart disease than apple-shaped people who carry fat in the abdomen. But in two studies, School of Medicine researchers report that body shape isn’t the only marker of risk. Excess liver fat appears to be the key to insulin resistance, cholesterol abnormalities and other problems that contribute to diabetes and cardiovascular disease.
Health care reform will not be highest priority
Barack Obama will need to act swiftly in his first 100 days as president to resolve the domestic crises facing the nation, but concerns about the economy mean that health care reform will not be the highest priority during that time, says leading public health experts at Washington University in St. Louis (WUSTL). Debra Haire-Joshu, Ph.D., professor of social work and medicine at WUSTL, and Timothy McBride, Ph.D., associate dean for public health at WUSTL’s George Warren Brown School of Social Work, are available to discuss health care legislation under Obama. Haire-Joshu served in Obama’s congressional office and McBride is part of the nationally representative Rural Policy Research Institute’s Health Panel.
Entrepreneurs vie for seed money in race for Olin Cup
The number of teams competing for the Olin Cup was whittled down to five finalists Nov. 19 in the “elevator pitch” stage of the race for $70,000 in seed money to start a new company. Three of the finalist teams are student-supported and in the running for an additional $5,000 prize given to the best […]
New sorority will be 18th Greek community on WUSTL campus
The Alpha Omicron Pi (AOPi) Fraternity will be the seventh National Panhellenic Conference organization for women to join the Greek community at Washington University, announced Ryan Jasen Henne, director of Greek Life. Colonization is slated for spring 2009. “The Greek Life Office and the existing Greek community is excited and optimistic that this organization will […]
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