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Islets isolated from a rat pancreasDiabetes researchers hoping to enlist the help of a protein targeted by cancer therapies have gained an important new insight into how the protein, known as mTOR, works in the pancreas. Ironically, diabetes researchers want to promote the capability of mTOR that oncologists want to shut down: its ability to cause cells to reproduce by dividing into copies of themselves.

Unraveling the mysteries of the human brain, and the mind it gives rise to, is within the reach of modern science, suggests a forthcoming issue of the journal Neuroscience. The special issue explores how sophisticated working memory processes — from the firing of a single neuron to the activation of multiple brain regions — help shape our understanding of the world, says issue co-editor Grega Repovs, a visiting post-doctoral fellow at Washington University in St. Louis. More…

Restricting calories may mean living longer.Can eating a low-calorie yet nutritionally balanced diet extend human life as it does in rodents? Preliminary research suggests it might, so researchers at the School of Medicine are launching a long-term study to find out.

Four women who hold influential public service leadership positions on the St. Louis area will offer career advice as part of a free public panel discussion on “Women in Public Service” at 4 p.m. April 19 in the Bryan Cave Moot Courtroom. Panelists include Catherine Hanaway, United States Attorney for the Eastern District of Missouri; Jennifer Joyce, Circuit Attorney City of St. Louis; Emmy McClelland, Director of Governmental Affairs at St. Louis Children’s Hospital; and Darlene Green, City of St. Louis Comptroller.

Finances will be a little less daunting this summer for five Washington University undergraduates pursuing unpaid public service internships in New York, Washington, D.C., and the villages of East Africa. They will be the first beneficiaries of a new Public Service Summer Stipend program sponsored by the University’s Richard A. Gephardt Institute for Public Service.

Maki & Associates, TokyoSaligman Family Atrium, Mildred Lane Kemper Art MuseumDownload high-resolution press images of Washington University’s new Sam Fox School of Design & Visual Arts, designed by Pritzker Prize-winning Japanese architect Fumihiko Maki.

Photo by Robert BostonOccupational therapy students learn to use different mobility devices.

Photo by Robert BostonEd Walter was among more than 70 employees honored for their years of service to WUSM.

The ECG in Multiple Myocardial Infarction and the Progression of Ischemic Heart Disease presents a unique view of the use of electrocardiograms.

The goal was set at $535,000, the highest in school history; money raised as of March 24 totaled $533,022 — less than $2,000 short.