NSAID increases liver damage in mice carrying mutant human gene

The large globules in the liver cells on the left are characteristic of alpha-1-antitrypsin deficiency. The image on the right shows normal liver cells.Research performed at the School of Medicine sheds light on the mechanisms that contribute to liver disease in alpha-1-AT deficiency patients. People with alpha-1-deficiency have a genetic mutation that can lead to emphysema at an early age and to liver damage. Using an experimental mouse model of the disorder, the researchers investigated the effects of a non-steroidal anti-inflammatory drug (NSAID) on liver injury.

Campus Watch

The following incidents were reported to University Police Nov. 7-13. Readers with information that could assist in investigating these incidents are urged to call 935-5555. This information is provided as a public service to promote safety awareness and is available on the University Police Web site at police.wustl.edu. Nov. 9 9:01 a.m. — A person […]

A stitch in time

Photo by Mary ButkusThe campus Knit-In brings together knitting enthusiasts from across campus and the community.
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