Science & Technology

A team of researchers from Washington University in St. Louis that includes Alan R. Templeton and the Israeli Institute of Technology (Technion) in Haifa has developed a technique to detect the ancestry of disease genes in hybrid, or mixed, human populations. The technique, called expected mutual information (EMI), determines how a set of DNA markers is likely to show the ancestral origin of locations on each chromosome.

Nanoparticles (yellow) show that a treated tumor (left) has less blood vessel growth than an untreated tumor.Anyone facing chemotherapy would welcome an advance promising to dramatically reduce their dose of these often harsh drugs. Using nanotechnology, researchers at the School of Medicine have taken a step closer to that goal. The researchers focused a powerful drug directly on tumors in rabbits using drug-coated nanoparticles.

Photo courtesy of USGSLevees are not infalliable.Midwesterners have to be wondering: Will April be the cruelest month? Patterns in the Midwest this spring are eerily reminiscent of 1993 and 1994, back-to-back years of serious flooding. Parallels this year include abnormally high levels of precipitation in late winter and early spring, early flooding in various regions, and record amounts of snow in states upstream. One thing Midwesterners have not learned is “geologic reality,” says Robert E. Criss, Ph.D., professor of earth and planetary sciences in Arts & Sciences at Washington University in St. Louis.

Below is a link to the Washington University news release about the U.S. News & World Report undergraduate rankings for 2004-05: http://news-info.wustl.edu/news/page/normal/3627.html To view a full listing of U.S. News magazine, book and Web-only rankings for 2004-05, please visit the U.S. News & World Report site: http://www.usnews.com/usnews/edu/college/rankings/rankindex_brief.php

FlanaganKathryn Flanagan, Ph.D., senior scientist and head of the James Webb Space Telescope (JWST) Mission Office at the Space Telescope Science Institute, will deliver the 2008 McDonnell Lecture at 7 p.m. Thursday, March 27, in Room 214 Wilson Hall on the Danforth Campus at Washington University in St. Louis.

British astronomer Jocelyn Bell Burnell will describe her landmark work in discovering the first pulsars at the Assembly Series at 11 a.m. on Wed., March 19 in Graham Chapel.

Human diseases and social networks seem to have little in common. However, at the crux of these two lies a network, communities within the network, and farther even, substructures of the communities. Weixiong Zhang, Ph.D., Washington University associate professor of computer science and engineering and of genetics, along with his Ph.D. student, Jianhua Ruan, has published an algorithm (a recipe of computer instructions) to automatically discover communities and their subtle structures in various networks.

Lemur population has declined sharply since the 1950s. Through education and conservation, a WUSTL expert hopes the trend will be reversed.Using satellite imagery, GIS and ecological and demographic data from the field, Robert W. Sussman, Ph.D., professor of anthropology in Arts & Sciences at Washington University in St. Louis, has studied the effects of deforestation on the ringtailed lemur population in Madagascar during the last forty years. He has determined that while causes of deforestation vary in different parts of the African island nation, the total lemur population has dropped by more than half since the 1950s.

The Earth’s orbital behaviors are responsible for more than just presenting us with a leap year every four years. According to Michael E. Wysession, Ph.D., associate professor of earth and planetary sciences in Arts & Sciences, parameters such as planetary gravitational attractions, the Earth’s elliptical orbit around the sun and the degree of tilt of our planet’s axis with respect to its path around the sun, have implications for climate change and the advent of ice ages.

Below is a link to the Washington University news release about the U.S. News & World Report undergraduate rankings for 2004-05: http://news-info.wustl.edu/news/page/normal/3627.html To view a full listing of U.S. News magazine, book and Web-only rankings for 2004-05, please visit the U.S. News & World Report site: http://www.usnews.com/usnews/edu/college/rankings/rankindex_brief.php