Scientists find a molecular clue to the complex mystery of auxin signaling in plants

Plants fine-tune the response of their cells to the potent plant hormone auxin by means of large families of proteins that either step on the gas or put on the brake in auxin’s presence. Scientists at Washington University have learned that one of these proteins, a transcription factor, has an interaction region that, like a button magnet, has a positive and negative face. Because of this domain, the protein can bind two other proteins or even chains of proteins arranged back-to-front.

From high school dropout to landing Curiosity on Mars: Adam Steltzner on how ‘Curiosity Changed My Life’

Nothing in Adam Steltzner’s younger years pointed to his becoming NASA’s chief engineer for the highly delicate landing of the Curiosity rover on Mars. He flunked high school geometry and dropped out to join a rock band. On March 26, Steltzner will tell how “Curiosity Changed My Life” for the Assembly Series. His presentation, which will begin at 6 p.m. in Graham Chapel, is free and open to the public.
Stand-up science

Stand-up science

The St. Louis FameLab, a science communication competition sponsored by National Geographic and NASA, recently gave young scientists a chance to present their science to nonscientists in three minutes. Efforts such as this are becoming increasingly common as scientists try to reconnect with the public. Some universities now require three-minute video presentations for every thesis or dissertation — or even for every published journal article.
Meditation on the brain​​

Meditation on the brain​​

For decades, neuroscientist Richard Davidson, PhD, has been conducting research on the positive impact of contemplative practices such as meditation on the brain. The work may have important ramifications for treating mental disorders. Davidson was on campus this month to deliver the Witherspoon Memorial Lecture on Religion and Science for the Assembly Series and a talk for the Department of Psychology.​
2014 Leopold Marcus lecture by Nobel laureate

2014 Leopold Marcus lecture by Nobel laureate

Roger Tsien, one of three chemists who won the Nobel Prize in Chemistry in 2008 for the discovery and development of green fluorescent protein, will give the Leopold Marcus lecture at Washington University in St. Louis. His talk, “Fluorescent Molecules for Fun and Profit,” is intended for a general audience and will take place at 4 p.m. Wednesday, March 12, in the Laboratory Sciences Building, Room 300. The talk is free and open to the public.
New drugs for bad bugs

New drugs for bad bugs

Washington University in St Louis chemist Timothy Wencewicz says we’ll stay ahead of antibiotic resistance only if we find drugs with new scaffolds, or core chemical structures. One promising candidate, an antibiotic made by a bacterium than infects plants, caught his attention because it contains an “enchanted ring,” the beta-lactam ring that is found in penicillin. In this drug candidate, however, it acts against a different target than the penicillins.
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