Science & Technology

A microbiology professor discusses antibiotic resistance and his lab’s efforts to help physicians fight antibiotic-resistant infections.

As everyone has probably heard, antibiotics are less and less effective and there are fewer and fewer replacements for failing drugs in the pipeline. So what would happen if you got an infection that was resistant to all the known antibiotics? Would you die, or is there something else doctors could try as a last […]

The National Science Foundation (NSF) has added a newly formed collaboration between Washington University in St. Louis and the University of Pennsylvania to its list of Science and Technology Centers (STC). The new center, one of just 12 nationally, will be supported by a $23.6 million NSF grant to study the mechanics of plant and animal cells. This deeper dive into how single cells function could transform both medicine and plant science.

Heralded on the cover of Time magazine in 2000 as a genetically modified (GMO) crop with the potential to save millions of lives in the Third World, Golden Rice is still years away from field introduction and even then, may fall short of lofty health benefits still cited regularly by GMO advocates, suggests a new study from Washington University in St. Louis.

We take so many things for granted. Why do trees grow only so tall and no taller? Why do some potatoes have those mysterious brown holes in them? And why do plants grow right-side up instead of upside-down? Eric Hamilton, PhD ’16, explores the question.

Genes inherited from mothers (matrigenes) and fathers (patrigenes) usually work harmoniously in the offspring. However, kin selection theory predicts these genes may be in conflict in interactions among relatives in which they are unequally represented (half-siblings). In honey bees, patrigenes are predicted to favor daughters that lay eggs themselves rather than remaining sterile and rearing their half-sisters’ offspring. An experimental test bears out this prediction.

Arpita Bose, PhD, assistant professor of biology in Arts & Sciences at Washington University in St. Louis, has been named a Packard Fellow, a prestigious distinction awarded to only 18 top young researchers nationwide this year. Bose plans to use the grant to work with unusual microbes that can take electrons directly from an outside source to draw down atmospheric carbon dioxide or make sustainable biofuels.

New research shows that an ancient protein that protects bacteria from bursting also helps pollen survive the dangerous transition from desiccated to hydrated once it lands on the female flower. But in pollen’s case, the protein has evolved to provide just the right amount of internal pressure: enough to power cell growth but not so much that the pollen bursts and dies.

DNA analysis of more than 1300 coconuts from around the world reveals that the coconut was brought under cultivation in two separate locations, one in the Pacific basin and the other in the Indian Ocean basin. What’s more, coconut genetics also preserve a record of prehistoric trade routes and of the colonization of the Americas.

Many food plants contain cyanogenic glycosides that can release cyanide when the food is eaten. What’s more, a greater proportion of food plants than plants in general are cyanogenic. WUSTL researcher Kenneth M. Olsen, PhD, offers an explanation of this toxic puzzle.