Medicine & Health

Neurons communicate at a synapseAs the nervous system develops early in life, it must create millions of synapses—small spaces between nerve cells across which the cells can communicate. Scientists have long speculated that these synapses are deliberately organized to place the structures that send messages on one cell directly across from the structures on another nearby nerve cell that receive those messages. School of Medicine researchers have provided the first experimental proof of this theory at the level of the nervous systems’ most fundamental unit: individual clusters of structures that send and receive signals.

Ellis utilizes genetic analysis to guide cancer therapy.A new breast cancer drug that has shown promise fighting a particularly tough type of tumor may become a viable option for cancer patients. Matthew Ellis, a WUSTL physician at the Siteman Cancer Center, has studied the medication, Lapatinib, since it first showed promise against breast cancer tumors. He is now conducting the final phase of trials for the drug. KSDK reporter Kay Quinn provides more details in the following St. Louis Post-Dispatch article.

Scientists have developed a new screening technique to help them look for genes that change patients’ responses to cancer drugs and other medications.

A recent study by James Fleshman, a colon and rectal surgery specialist at the School of Medicine, showed that minimally invasive colon cancer surgery allows patients to heal faster and experience less pain. KSDK reporter Kay Quinn tells more about the procedure in the following St. Louis Post-Dispatch article.

Everyone sweats, but it’s unlikely many people ever consider the social and economic impact of our bodies’ built-in air conditioning system. With summer’s hottest days likely still to come, Michael Heffernan, assistant professor of dermatology at the School of Medicine, helps St. Louis Post-Dispatch writer Jeff Daniels take a closer look at this hot topic.

Glowing firefly light reveals interacting proteins.Radiologists at the School of Medicine have developed a first-of-its-kind noninvasive imaging technique that allows them to watch two proteins interacting in live animals. The technique genetically fuses proteins of interest with carefully cleaved sections of luciferase, the protein fireflies use to create light.

Jan Brunstrom demonstrates martial arts moves with cerebral palsy patient Emma Price.A comprehensive care plan involving sports, physical fitness and strength training is key to helping children with cerebral palsy grow into active adults, according to WUSTL pediatric neurologist Jan Brunstrom. Not only are athletic activities fun for children, but they can also reduce the need for traditional therapy.

A five-year, $2.5 million grant from the National Institute for Occupational Safety and Health may help employers determine which employees are more likely to get carpal tunnel syndrome and other hand, wrist and elbow problems. School of Medicine physician Bradley A. Evanoff is leading the study.

H. pylori bound to stomach tissueScientists working to develop a vaccine for the bacterium Helicobacter pylori, the primary cause of ulcers and a contributor to stomach cancers, have uncovered new intricacies in the way the bacterium sticks to the lining of the human stomach.

Scientists have known for years that eating less tends to make animals live longer, but no one is quite sure why. Several School of Medicine researchers studying the effects of caloric restriction on humans may help provide an answer to that question. This story was written by Tina Hesman and published by the St. Louis Post-Dispatch.