New asthma drug holds hope for some

A new medication can reduce emergency room visits and improve the overall quality of life for moderate to severe asthma sufferers, according to a study by researchers from the School of Medicine and St. Louis University. Learn more about the new drug in the following St. Louis Post-Dispatch story.

Enhancing innate immunity improves Crohn’s disease symptoms

Like throwing oil on a fire or prescribing a high cholesterol diet for heart patients, gastroenterologists traditionally have believed that it would not be a good idea to stoke up the body’s immune system to treat Crohn’s disease. Most treatments for Crohn’s, an autoimmune disorder, are geared to suppress the immune response, but a new study demonstrates that stimulating innate immunity also is effective at improving symptoms of the intestinal disorder.

Disabling gene defuses rheumatoid arthritis in mice

Scientists studying mice have identified a gene that allows immune cells known as neutrophils to protect themselves from the inflammatory chemicals they secrete. Researchers at the School of Medicine showed that knocking the gene out in mice prevented the development of an arthritis-like disorder by making the neutrophils victims of their own damaging secretions.
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