Medicine & Health

B cellsScientists at the School of Medicine have identified a protein that can reduce the chances immune B cells will erroneously attack the body’s own tissues, causing autoimmune disorders like lupus, allergies, arthritis and diabetes. The protein is the first of its kind to be identified in B cells and could provide scientists with a new target for treating such conditions.

Surgeons cut and reposition hip bones to reduce pain.When an older person has a hip problem, surgeons often replace the damaged hip with an artificial one. But that’s not a good option for someone in their 20s or 30s, so orthopaedic surgeons at the School of Medicine are repairing damage to the hip to prevent arthritis without having to replace the hip joint.

A biomedical engineer at WUSTL has determined love taps are better than love jolts in addressing defibrillation.When it comes to affairs of the heart, love taps are preferred over love jolts. That is the result of a team of heart researchers including Igor Efimov, Ph.D., associate professor of biomedical engineering at Washington University in St. Louis, trying to effect a better implantable heart defibrillator. Efimov and his colleagues have modeled a system where an implantable heart defibrillator focuses in on rogue electrical waves created during heart arrhythmia and busts up the disturbance, dissipating it and preventing cardiac arrest.

Ritonavir may slow bone loss in AIDS patients.In a collaborative study initiated by their clinical colleagues, scientists at the School of Medicine have shown that the AIDS drug ritonavir suppresses the creation and activity of cells that dismantle bone, potentially slowing bone loss and lowering the risk of osteoporosis in AIDS patients. The findings may encourage clinicians to consider permanently keeping ritonavir or a similar bone-sparing drug in the changing mixture of treatments for AIDS patients.

Studying elderly people with mild to moderately elevated blood pressure, researchers at the School of Medicine have found that exercise is just as effective as blood pressure medicine at reducing heart mass and the thickness of the heart wall. Exercise also provided benefits that blood pressure medicine did not, such as lowering an individual’s risk of developing diabetes.

Philip Stahl, prominent cell biologist and physiologist and Jonathan Turner, internationally recognized for his accomplishments in computer networks and telecommunications, will receive Washington University’s 2004 Faculty Achievement Awards and summarize their scholarly work at an awards ceremony, as part of the Assembly Series on Sept. 23.

St. Louis Jewish LightFlanceFor retired physician I. Jerome Flance, more than 60 years of helping people as a doctor and teacher wasn’t quite enough. So six years ago, at age 87, he accepted the appointment of special associate for community redevelopment and began what is planned to be a 10-year project to revitalize the Forest Park Southeast neighborhood. Read more in the following article published by the St. Louis Jewish Light Simcha magazine.

St. Louis Post-DispatchOsteoporosis is the cause of more than 1 million bone fractures each year — injuries which can be devastating to the elderly. The condition, however, seems to be spreading among the young, even those in prime physical shape. Kathryn Diemer, director of the Bone Health Program, talks about the increase of cases in younger adults in the following St. Louis Post-Dispatch article, which focuses on a 34-year-old marathon runner.

The season for sneezin’ is here.Ragweed pollen counts appear to have peaked in early September this year, nearly a month later than usual. H. James Wedner, chief of the division of allergy and immunology, comments on what this means for allergy sufferers in this article by Tina Hesman of the St. Louis Post-Dispatch.

Why do some people live longer?Researchers at the School of Medicine will head an ambitious study of people who live exceptionally long and healthy lives to identify the factors that account for their longevity. A team led by Michael Province, Ph.D., professor of biostatistics and genetics, received a $4 million grant from the National Institute on Aging to establish a Data Management and Coordinating Center for the Exceptional Longevity Family Study.