Medicine & Health

The gray shading shows the areas surveyed for the study.A comparison of residential areas in the St. Louis region reveales that late middle-aged and older African-Americans who live in rundown neighborhoods with poor air and street quality are three times more likely to develop difficulties walking, standing, or lifting than those in cleaner, better-maintained areas.

Concerns over biopiracy have fueled urgent calls for a new system of legal protection for indigenous biological materials and knowledge. Detractors of the current patent systems say that the knowledge of traditional cultures and communities does not readily fit into the industrialized world’s definition of intellectual property (IT); critics argue that existing laws basically promote the interests of the industrialized world. However, intellectual property and technology law expert Charles McManis, J.D., disagrees. More…

The Bush administration’s plan to push through health savings accounts is limited in how much it can lower healthcare costs, according to a business professor in the Olin School of Business at Washington University. He says that health savings accounts could work for some things – if the relationship between most doctors and patients changes, and if there were greater acceptance of the variety of ways to keep people healthy. More…

Scientists have completed an extensive study of more than 3,000 patients who received a promising anti-inflammatory drug, natalizumab, that was linked to three cases of a serious brain infection in large clinical trials halted in early 2005.

A program designed by the Weight Management Center at the School of Medicine and the YMCA of Chesterfield has helped the Garcia family from Chesterfield lose roughly 105 pounds. The Family Lifestyle Intervention Program (FLIP) is designed to show families how to get healthy together through supervised exercise, counseling and education.

Small-scale preliminary trials suggested that careful control of blood pressure could possibly delay or even prevent kidney failure in patients with polycystic kidney disease (PKD), which affects more than 600,000 people in the United States.

Washington University has a long tradition of undergraduate participation in research, one developed further by programs created by Sarah Elgin, Ph.D., professor of biology; biochemistry and molecular biophysics; and education in Arts & Sciences with financial support from the Howard Hughes Medical Institute.

Biotech innovations pop up every day. From medicines developed by large companies to ingenious solutions worked out by individuals in university labs, new technologies are poised to enter the marketplace. The question is, are patents helping or hurting this process? “Patents are essential to bring biotechnology innovations from everyone — not just well-funded corporations — to the people,” says F. Scott Kieff, J.D., associate professor of law at Washington University in St. Louis. “Without patents, the biotech marketplace in basic science takes on the nature of something like an old boys’ club in which personal attributes such as fame, prestige, and even gender and race, govern what exchanges take place; and the addition of patents gives many more people a way to play in that game.”

Growing biopiracy concerns have fueled urgent calls for a new system of legal protection for traditional knowledge. Detractors of the current patent systems say that the traditional knowledge of indigenous peoples and local communities does not readily fit into the existing rules of the industrialized world and that these rules basically promote the interests of the industrialized world. However, Charles McManis, J.D., IP and technology law expert and the Thomas and Karole Green Professor of Law at Washington University in St. Louis, argues that “at least in the short run, existing intellectual property regimes offer the most realistic avenue for securing effective legal protection for traditional knowledge holders.”

Chromosomal damage results in fusion (bottom).Inactivating a protein called mammalian Rad9 could make cancer cells easier to kill with ionizing radiation, according to research at the School of Medicine. The researchers found that Rad9, previously considered a “watchman” that checks for DNA damage, is actually a “repairman” that fixes dangerous breaks in the DNA double helix.