Computerized atlas highlights ‘plethora’ of changes in brain disorder

Abnormal folding patterns of the cerebral cortex in Williams Syndrome are displayed on a lateral view (left) and midline view (right) of a ‘surface-based’ atlas.A computerized atlas has brought unprecedented sensitivity to the search for brain structure changes in a genetic condition known as Williams syndrome, revealing 33 abnormalities in the folding of the brain’s surface. The disorder, which occurs in 1 in every 20,000 births, impairs visual and spatial skills but preserves musical ability and sociability.

Coffee, black, decaf and a little llama on the side

Assab and Massawa, the two camels that produced antibodies for the caffeine testThree llamas and two camels have provided a way to tell whether your waiter swapped regular coffee for decaf in your after-dinner cup. Using the heat-resistant antibodies these camels and llamas make, researchers at the School of Medicine are developing a quick test for caffeine that works even with hot beverages. The researchers plan to adapt their technology to a simple test (“dipstick”) that can be used to check for caffeine in a variety of drinks.

Children, adults with breathing problems can attend free asthma screening

If you’ve regularly been coughing, wheezing or short of breath, you may want to get tested for asthma at the Saint Louis Science Center on Saturday, May 20. As part of a nationwide program, Washington University School of Medicine and Barnes-Jewish Hospital physicians will be at the Science Center to test lung function and answer questions about asthma. The screenings are free.

May 2006 Radio Service

Listed below are this month’s featured news stories. • Diabetes and depression (week of May 3) • Lessen frailty by losing weight (week of May 10) • Smokers get more jolts (week of May 17) • Sunscreen is more than just SPF (week of May 24) • Tumor location doesn’t really matter (week of May 31)

Research finds sugar required for healthy brain development

ZebrafishTo learn more about how glucose affects human development, Washington University researchers have developed the first vertebrate model of the role of glucose in embryonic brain development. The model is made up of zebrafish. Their transparent embryos develop similarly to humans, except that they grow outside of the mother’s body, where development can be more easily observed. The model provides the foundation for and insight into the roles of nutrition and genetics in human birth defects. The research also may have implications for patients with neurodegenerative diseases such as Parkinson’s. More…
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