Medicine & Health

Washington University today joined a consortium of leading scientific and medical institutions around the country to warn Congress that persistent flat-funding of biomedical research could thwart advances in treatments for such diseases as cancer and Alzheimer’s disease. Following today’s Senate Appropriations Labor-HHS Committee hearing on funding for the National Institutes of Health (NIH), Washington University and the eight other institutions issued a report at a Capitol Hill press conference on funding for U.S. medical research.

The basketball teams still need to play their way in, but a team of physicians already knows they’ll be on hand for the NCAA basketball tournament’s regional championship next weekend in St. Louis. The sports medicine specialists in the Department of Orthopaedic Surgery at the School of Medicine will coordinate care at the NCAA Division I Men’s Midwest Regional March 23-25 at the Edward Jones Dome.

A team of investigators at the School of Medicine and other centers around the United States is evaluating dietary supplements to determine if they can prevent some of the damage from age-related macular degeneration (AMD), a leading cause of blindness in Americans over the age of 65.

Neuroscientists at the School of Medicine have linked a common post-stroke disability to impaired communication between brain regions. In the March 15 issue of Neuron, researchers report a tight correlation between the degree to which communication was blocked and the severity of patients’ symptoms.

Listed below are this month’s featured news stories. • Side effects of AIDS medications (week of Mar. 7) • Belly fat’s role in disease (week of Mar. 14) • Aneurysm-causing enzyme identified (week of Mar. 21) • Smoking delays ligament healing (week of Mar. 28)

An illustration from “When Grandpa Comes Home: A Story About Stroke,” an online book that teaches children how to cope when a relative suffers a strokeSpeedy treatment is essential to saving lives and preventing brain damage during a stroke. But the rapid pace of events also can leave patients and family members confused about what has happened and what to expect. That’s especially true for children whose parents or grandparents have a stroke. Now an online book is available to teach children about strokes at www.strokecenter.org/patients. More…

On the battlefield, a soldier’s hearing can be permanently damaged in an instant by the boom of an explosion, and thousands of soldiers returning from Iraq have some permanent hearing loss. But what if soldiers could take a pill before going on duty that would prevent damage to hearing? Research at Washington University School of Medicine in St. Louis suggests a medicinal form of hearing protection may someday be a possibility. More…

An abdominal MRI scan showing the locations of subcutaneous and visceral fatAs scientists learn more about the key role of inflammation in diabetes, heart disease and other disorders, new research from Washington University School of Medicine in St. Louis suggests that fat in the belly may be an important promoter of that inflammation. It’s well known that excess fat is associated with disease, but the researchers have confirmed that fat cells inside the abdomen are secreting molecules that increase inflammation. It’s the first evidence of a potential mechanistic link between abdominal fat and systemic inflammation. More…

Parag Parikh and Kristen Lechleiter set up the 4D Phantom to simulate the motion of tumors in the lung.Tumors that move, such as those in the lung — which can change position during each breath — are a special problem for radiation oncologists. A group at Washington University School of Medicine in St. Louis has studied the way lung tissues move during breathing in hopes of improving radiation as a treatment for lung cancer. More…

A compound that halts nerve cell activity when exposed to light glows in this image of two nerve cells.Brain activity has been compared to a light bulb turning on in the head. Scientists at the School of Medicine have reversed this notion, creating a drug that stops brain activity when a light shines on it. The new compound activates the same receptor used by many anesthetics and tranquilizers, making it harder for a brain cell to respond to stimulation. The drug may some day be used to treat epilepsy.