Medicine & Health

Photo by David KilperLarry A.Taber, Ph.D., (left) the Dennis and Barbara Kessler Professor of Biomedical Engineering, and Philip Bayly, Ph.D., the Hughes Professor of Mechanical Engineering, employ a microindentation device to measure the mechanical properties of embryonic hearts and brains. The researchers are examining mechanical and developmental processes that occur in the folding of the brain’s surface, or cortex, which gives the higher mammalian brain more surface area (and more intellectual capacity) than a brain of comparable volume with a smooth surface.

Image courtesy of the BBCWhat good is longevity if you end up looking like this? WUSTL biologist Stan Braude, working on a book about the critters, says the naked mole rat is being studied for its tendency to live a long life.Who would have thought that the secrets to long life might exist in the naked, wrinkled body of one of the world’s ugliest animals? Probably not many, but current research may be leading seekers of the Fountain of Youth to a strange little beast — the naked mole rat.

The School of Medicine is participating in the largest study of child and human health ever conducted in the United States. The National Institutes of Health has selected the city of St. Louis and Macoupin County, Ill., as sites for the National Children’s Study, an extensive population-based study looking at the health and development of children by following them from before birth to adulthood.

Although the causes of Alzheimer’s disease are not completely understood, amyloid-beta (A-beta) is widely considered a likely culprit — the “sticky” protein clumps into plaques thought to harm brain cells. But now researchers at the School of Medicine have uncovered evidence strengthening the case for another potential cause of Alzheimer’s. The finding also represents the first time scientists have found a connection between early- and late-onset Alzheimer’s.

Engineers at Washington University in St. Louis are finding common ground between the shaping of the brain and the heart during embryonic development. Larry A.Taber, Ph.D., the Dennis and Barbara Kessler Professor of Biomedical Engineering, and Philip Bayly, Ph.D., the Hughes Professor of Mechanical Engineering, are examining mechanical and developmental processes that occur in the folding of the brain’s surface, or cortex, which gives the higher mammalian brain more surface area (and hence more intellectual capacity) than a brain of comparable volume with a smooth surface.

A little health information is not enough to help obese children get into better shape, according to a recent analysis. Moreover, children who do not receive an offer for intervention or who receive information only tend to experience weight gains. Children given guidance that is more direct get into better shape, according to the review. “Providing information is a necessary component, but it’s not sufficient,” said Denise Wilfley, Ph.D., lead author of the study and professor of psychiatry at the School of Medicine.

David Kilper/WUSTL Photo(L-R) Larry Taber, postdoctoral researcher Gang Xu and Philip Bayly examine brain and heart cells to learn something of the mechanics involved in brain folding.Engineers at Washington University in St. Louis are finding common ground between the shaping of the brain and the heart during embryonic development. Larry A.Taber, Ph.D., the Dennis and Barbara Kessler Professor of Biomedical Engineering, and Phillip Bayly, Ph.D., Hughes Professor of Mechanical Engineering, are examining mechanical and developmental processes that occur in the folding of the brain’s surface, or cortex, which gives the higher mammalian brain more surface area (and hence more intellectual capacity) than a brain of comparable volume with a smooth surface.

Active guidance is key when helping kids make diet and exercise changes, according to a new study.A little health information is not enough to help obese children get into better shape, according to a recent analysis. Moreover, children who do not receive an offer for intervention or who receive information only tend to experience weight gains. Children given guidance that is more direct get into better shape, according to the review. “Providers make the assumption that providing information leads to changes,” said Denise Wilfley, Ph.D., lead author and professor in the department of psychiatry at the Washington University School of Medicine in St. Louis. “Providing information is a necessary component, but it’s not sufficient.”

CottlerLinda Cottler, professor of epidemiology in psychiatry at the School of Medicine, has been named president-elect of the American Psychopathological Association (APPA). She will serve as its president in 2010, the organization’s centennial year.

The School of Medicine has received a five-year, $4.6 million grant to establish an interdisciplinary career development training program for physical and occupational therapists. The grant is from the National Center for Medical Rehabilitation Research of the National Institute of Child Health and Human Development and the National Institute of Neurological Disorders and Stroke.