Medicine & Health

Whether it’s needed to track the activity of a drug, the growth of a tumor or the progress of a medical disorder, high-tech imaging equipment often is an essential component of advanced clinical research. Unfortunately, patient care typically keeps these machines and the doctors who run them jammed with activity, often making it necessary to fit in research activities late at night or on the weekends.

Richard K. Wilson, Ph.D., is leading efforts to sequence the corn genome.University scientists have begun to unlock the genetic secrets of corn, a crop vital to U.S. agriculture. The researchers have completed a working draft of the corn genome, an accomplishment that should accelerate efforts to develop better crop varieties to meet society’s growing demands for food, livestock feed and fuel.

A better drug for osteoporosis wouldn’t just preserve patients’ old bone structure; it would help fortify their weakened bones with new bone material. Such a drug could be on the horizon because of research at the School of Medicine that has uncovered new information about how to amplify the bone formation process.

The complete collection of genes — the genome — of a moss has been sequenced, providing scientists an important evolutionary link between single-celled algae and flowering plants.

Scientists at the School of Medicine have linked a mutation in a gene known as TDP-43 to an inherited form of amyotrophic lateral sclerosis (ALS), the neurodegenerative condition often called Lou Gehrig’s disease. Researchers found the connection intriguing because studies by other groups have revealed abnormalities in the TDP-43 protein in both sporadic and inherited ALS, as well as in several other neurodegenerative disorders.

Below is a link to the Washington University news release about the U.S. News & World Report undergraduate rankings for 2004-05: http://news-info.wustl.edu/news/page/normal/3627.html To view a full listing of U.S. News magazine, book and Web-only rankings for 2004-05, please visit the U.S. News & World Report site: http://www.usnews.com/usnews/edu/college/rankings/rankindex_brief.php

Below is a link to the Washington University news release about the U.S. News & World Report undergraduate rankings for 2004-05: http://news-info.wustl.edu/news/page/normal/3627.html To view a full listing of U.S. News magazine, book and Web-only rankings for 2004-05, please visit the U.S. News & World Report site: http://www.usnews.com/usnews/edu/college/rankings/rankindex_brief.php

Subtle malformations in the brains of patients with schizophrenia also tend to occur in their healthy siblings, according to investigators at the Silvio Conte Center for the Neuroscience of Mental Disorders at the School of Medicine. Shape abnormalities were found in the brain’s thalamus. The researchers performed brain MRI scans in 25 patients with schizophrenia and their non-affected siblings and compared the scans with those of 40 healthy volunteers and their siblings.

Experts in alcoholism and suicide from around the United States will present their research Feb. 21 at the 8th Annual Samuel B. Guze Symposium on Alcoholism at the School of Medicine. This year’s event focuses on “Alcohol, Suicide and Suicidality.” The program is intended for physicians, psychologists, social workers, teachers, policy makers, other health professionals and members of the community.

Therapists and eating disorders specialists at the School of Medicine are joining investigators at a handful of sites around North America to evaluate anorexia nervosa treatments. Only 25 percent of anorexia patients recover completely, and the goal of this study is to improve those odds.