Medicine & Health

Frustrated by the slow pace of new drug development for a condition that causes pediatric brain tumors, a neurologist at the School of Medicine decided to try to fine-tune the animal models used to test new drugs. Instead of studying one mouse model of the disease causing the brain tumors, the laboratory of David Gutmann, M.D., Ph.D., the Donald O. Schnuck Family Professor of Neurology, evaluated three and found that one of most closely mimicked what is seen in children who develop brain tumors.

Physicians and glaucoma researchers in the Department of Ophthalmology and Visual Sciences at the School of Medicine will join eye-care professionals around the world on March 6, 2008, to observe the first World Glaucoma Day. The global initiative is aimed at raising awareness of glaucoma, a disease of the optic nerve that affects 65 million people worldwide.

Jean Schaffer has been named the Virginia Minnich Distinguished Professor in Medicine at the School of Medicine. Chancellor Mark S. Wrighton made the announcement with Larry Shapiro, executive vice chancellor for medical affairs and dean of the School of Medicine.

Whether it’s needed to track the activity of a drug, the growth of a tumor or the progress of a medical disorder, high-tech imaging equipment often is an essential component of advanced clinical research. Unfortunately, patient care typically keeps these machines and the doctors who run them jammed with activity, often making it necessary to fit in research activities late at night or on the weekends.

Richard K. Wilson, Ph.D., is leading efforts to sequence the corn genome.University scientists have begun to unlock the genetic secrets of corn, a crop vital to U.S. agriculture. The researchers have completed a working draft of the corn genome, an accomplishment that should accelerate efforts to develop better crop varieties to meet society’s growing demands for food, livestock feed and fuel.

A better drug for osteoporosis wouldn’t just preserve patients’ old bone structure; it would help fortify their weakened bones with new bone material. Such a drug could be on the horizon because of research at the School of Medicine that has uncovered new information about how to amplify the bone formation process.

The complete collection of genes — the genome — of a moss has been sequenced, providing scientists an important evolutionary link between single-celled algae and flowering plants.

Scientists at the School of Medicine have linked a mutation in a gene known as TDP-43 to an inherited form of amyotrophic lateral sclerosis (ALS), the neurodegenerative condition often called Lou Gehrig’s disease. Researchers found the connection intriguing because studies by other groups have revealed abnormalities in the TDP-43 protein in both sporadic and inherited ALS, as well as in several other neurodegenerative disorders.

Below is a link to the Washington University news release about the U.S. News & World Report undergraduate rankings for 2004-05: http://news-info.wustl.edu/news/page/normal/3627.html To view a full listing of U.S. News magazine, book and Web-only rankings for 2004-05, please visit the U.S. News & World Report site: http://www.usnews.com/usnews/edu/college/rankings/rankindex_brief.php

Below is a link to the Washington University news release about the U.S. News & World Report undergraduate rankings for 2004-05: http://news-info.wustl.edu/news/page/normal/3627.html To view a full listing of U.S. News magazine, book and Web-only rankings for 2004-05, please visit the U.S. News & World Report site: http://www.usnews.com/usnews/edu/college/rankings/rankindex_brief.php