Sleep switch found in fruit flies

Rather than count sheep, drink warm milk or listen to soothing music, many insomniacs probably wish for a switch they can flick to put themselves to sleep. Scientists at Washington University School of Medicine in St. Louis, including Paul Shaw, PhD, have discovered such a switch in the brains of fruit flies.

Campus Authors: Charles F. Zorumski, MD, and Eugene H. Rubin, MD, PhD

Psychiatry and Clinical Neuroscience: A Primer, is the second book in 18 months from Charles F. Zorumski, MD, the Samuel B. Guze Professor and Head of Psychiatry, and Eugene H. Rubin, MD, PhD, professor of psychiatry. It is about how the brain works and what the growing understanding of neuroscience will mean to future diagnosis and treatment of psychiatric illnesses. 

Getting control of the control group

Lifestyles and emotions play important roles in many medical illnesses, and when scientists study potential treatments to help people stop smoking, get more exercise, overcome depression or improve their diet, they often compare patients who get a certain treatment to others who don’t. Researchers at Washington University School of Medicine in St. Louis, led by Ken Freedland, MD, say to accurately measure a new therapy’s the effectiveness, it is critical to carefully define comparison — or control — groups in those studies.  

Scientists find gene vital to nerve cell development

The body’s ability to perform simple tasks like flex muscles or feel heat, cold and pain depends, in large part, on myelin, an insulating layer of fats and proteins that speeds the propagation of nerve cell signals. Now, scientists have identified a gene in mice that controls whether certain cells in the peripheral nervous system can make myelin. Called Gpr126, the gene encodes a cellular receptor that could play a role in diseases affecting peripheral nerves.
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