Weight-loss surgery cost-effective for all obese

Bariatric surgery is not only cost-effective for treating people who are severely obese, but also for those who are mildly obese, according to a new study from Washington University School of Medicine in St. Louis. The findings support making bariatric surgery available to all obese people, the researchers say.

Finding STARS

Steven Mumm, PhD (left), research associate professor of medicine, works in his lab at the School of Medicine with Adela Cajic, a rising senior at Affton High School and a participant in the Students and Teachers as Research Scientists (STARS) program. STARS pairs academically talented high school juniors and seniors in the St. Louis area with scientists at five research institutions for a six-week apprenticeship in laboratories, including those on the Danforth and Medical campuses.

The biology behind alcohol-induced blackouts

Neuroscientists at Washington University School of Medicine in St. Louis have identified the brain cells involved in alcohol-related blackouts and the molecular mechanism that appears to underlie them. Alcohol interferes with key receptors in the brain, which in turn manufacture steroids that inhibit long-term potentiation, a process that strengthens the connections between neurons and is crucial to learning and memory. 

Surprising culprits behind cell death from fat and sugar overload

Excess nutrients, such as fat and sugar, don’t just pack on the pounds but can push some cells in the body over the brink. Unable to tolerate this “toxic” environment, these cells commit suicide. Now, scientists at Washington University School of Medicine in St. Louis have discovered three unexpected players that help a cell overloaded with fat initiate its own demise.
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