Medicine & Health

Some 200 U.S. scientists at Washington University School of Medicine in St. Louis and elsewhere detail findings from the most comprehensive census of the microbial make-up of healthy humans.

Researchers have identified the primary player of the biochemical bugle call that musters the body’s defenders against viral infection. Scientists at Washington University School of Medicine in St. Louis have shown that a key molecule, MDA5, is essential for producing enough interferon (the bugle call) to rally virus-fighting cells during certain viral infections.

Robert J. Glaser, Emeritus Trustee and former Washington University School of Medicine faculty member, died Thursday, June 7, 2012, at his home in Palo Alto, Calif. He was 93.

Studying mice and humans, researchers at Washington University School of Medicine in St. Louis and their collaborators in Paris have identified two proteins that are required to maintain a supply of stem cells in the developing kidney. The work is a small step toward the future goal of growing kidney stem cells in the lab.

Gregory P. Magarian, JD, professor of law, and Timothy D. McBride, PhD, professor of public health, both at Washington University in St. Louis, are available for expert commentary on the Supreme Court’s Affordable Care Act decision.

M. Alan Permutt, MD, professor of medicine and of cell biology and physiology at Washington University School of Medicine in St. Louis, died of cancer Sunday, June 10, 2012, in St. Louis. He was 72.

Decoding the DNA of patients with advanced breast cancer has allowed scientists to identify distinct cancer “signatures” that could help predict which women are most likely to benefit from estrogen-lowering therapy, while sparing others from unnecessary treatment.

Kevin Black’s family didn’t have any physicians in it. Well, one of his great-great-grandfathers had a medical license back in the late 1800s, but he had no formal training — and Black himself wasn’t planning on medical school. But during his first year of college, a teacher helped change his career plans.

The 2-1-1 phone information and referral system could be a key partner in efforts to reduce cancer disparities affecting low-income and racial and ethnic minorities in the U.S., finds a new study by Jason Purnell, PhD, assistant professor of public health at the Brown School at Washington University in St. Louis.

People who restrict their caloric intake in an effort to live longer have hearts that function more like those in people who are 20 years younger. Researchers at Washington University School of Medicine in St. Louis have found that a key measure of the heart’s ability to adapt to physical activity, stress and other factors, doesn’t decline nearly as rapidly in people who have significantly restricted their caloric intake.