Medicine & Health

Charged atoms, or ions, move through tiny pores, or channels, embedded in cell membranes, generating the electrical signals that allow cells to communicate with one another. In new research, scientists have shown how an unusual protein plays a key role in temporarily blocking the movement of ions through these channels. Preventing ions from moving through the channel gives cells time to recharge so that they can continue firing.

David Warren, MD, medical director for infection control at the School of Medicine and Barnes-Jewish Hospital, works diligently to prevent infections, but when they do occur, he pulls out all the stops to halt their spread. And in a world that is increasingly interconnected, Warren also must keep abreast of emerging global epidemics that have the potential to wreak havoc if there’s a local outbreak.

Scientists studying the way Alzheimer’s disease takes root in the brain have identified important new similarities between a mouse model and human Alzheimer’s. Researchers at Washington University School of Medicine in St. Louis have shown that brain plaques in mice are associated with disruption of the ability of brain regions to network with each other.

Scientists have identified the first gene directly linked to the most common form of psoriasis, a chronic skin condition. The research shows that rare mutations in the CARD14 gene, when activated by an environmental trigger, can lead to plaque psoriasis. This type of psoriasis accounts for 80 percent of all cases.

New research by scientists at the School of Medicine provides evidence to explain why some people are more prone to develop kidney stones than others. The discovery opens the door to finding effective drug treatments and a test that could assess a person’s risk of kidney stones.

The Washington University Neurofibromatosis (NF) Center at will host its first research symposium May 4. The event will focus on clinical and basic science research on neurofibromatosis 1, an inherited condition that increases risk of brain tumors in children and adults.

When a child has autism, siblings are also at risk for the disorder. New research from Washington University School of Medicine in St. Louis shows that the genetic reach of the disorder often extends to half siblings as well. The discovery is giving scientists new clues to how autism is inherited.

Tread the Med, the School of Medicine’s wellness and walking initiative, kicks off its “Most Valuable Walker” campaign from 11 a.m.- 1 p.m. April 26 in Hudlin Park with a ceremonial first walk led by Larry J. Shapiro, MD, executive vice chancellor for medical affairs and dean of the School of Medicine; James P. Crane, MD, associate vice chancellor for clinical affairs, and Fredbird, mascot of the St. Louis Cardinals.

Earth Day activities at the School of Medicine will take place from 10:30 a.m.-1:30 p.m., Thursday, April 19. All faculty, staff and students are encouraged to take part to learn about energy conservation and alternative energy; recycling; gardening and water conservation; and transportation and clean air.

The Siteman Cancer Center at Washington University School of Medicine and Barnes-Jewish Hospital is seeking patients for a clinical study to determine the best treatment for patients with early-stage lung cancer who also have breathing problems. The study focuses on patients with the most common type of lung cancer, non-small cell lung cancer.