Investigational diabetes drug may have fewer side effects

Drugs for type 2 diabetes can contribute to unwanted side effects, but Washington University researchers have found that in mice, an investigational drug appears to improve insulin sensitivity without side effects. The medicine works through a different pathway, which could provide additional targets for treating insulin resistance and diabetes.

Lack of competition could hike costs in health insurance exchanges

A new study suggests that health insurance exchanges, a key provision of the Affordable Care Act passed in 2010, may need to be monitored by policymakers to make sure there is sufficient competition between private insurance plans. In the study, published in Health Affairs, Timothy McBride, PhD, professor and associate dean for public health at the Brown School at Washington University in St. Louis, examined the insurance premiums, availability of plans and enrollment levels under the Federal Employees Health Benefits Program (FEHBP). “From its inception, the health reform legislation used the structure of the FEHBP to guide the design of these exchanges,” McBride says.

Genes predict if medication can help you quit smoking

A new study shows the same gene variations that make it difficult to stop smoking also increase the likelihood that heavy smokers will respond to nicotine-replacement therapy and drugs that thwart cravings. The finding suggests it may one day be possible to predict which patients are most likely to benefit from drug treatments for nicotine addiction.
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