Medicine & Health

Researchers have identified a genetic error responsible for some cases of a rare childhood leukemia with a poor prognosis.

The School of Medicine has received a $50 million grant to help speed the translation of scientific discoveries into improvements in human health. The grant supports the School of Medicine’s Institute of Clinical and Translational Sciences, led by Bradley A. Evanoff, MD.

Studying premature babies prior to their release from the NICU, researchers at Washington University School of Medicine in St. Louis have identified developmental differences between those preemies and babies born at full term. Their work points to opportunities for therapeutic interventions — even in the first few weeks of life — that might improve long-term outcomes for the preemies.

Researchers at Washington University School of Medicine in St. Louis have received a $9 million grant to investigate blood-clotting disorders. From heart attacks and strokes to uncontrolled bleeding, clotting disorders cause more deaths each year in the United States than all types of cancer combined.

Investigators at Washington University and The Scripps Research Institute have announced the launch of a “Global Metabolomic Initiative” to facilitate meta-analyses on studies of the metabolism of bacteria, yeast, plants, animals and people. Although metabolomics has existed as a discipline for only a decade, it has already provided insights into many difficult-to-treat diseases, including chronic pain. Many more are expected to fall out of the meta-analyses.

​The Program in Physical Therapy at Washington University School of Medicine in St. Louis has received a five-year, $4.6 million grant to continue an interdisciplinary training program for occupational and physical therapists that began in 2007.

By decoding the genomes of more than 1,000 people whose homelands stretch from Africa and Asia to Europe and the Americas, scientists have compiled a detailed catalog of human genetic variation to find the genetic roots of rare and common diseases in populations worldwide. ​

Researchers at the School of Medicine have received a five-year, $5.3 million grant to explore the way gender and age influence susceptibility to urinary tract infections, one of the most common bacterial infections.

School of Medicine researchers have received a five-year, $2.7 million grant to detect and analyze differences in the brains of children with a rare illness, Wolfram syndrome. The disorder includes a severe form of diabetes, hearing and vision loss and kidney problems. Patients also eventually lose muscle control and coordination from brain degeneration.

Resveratrol, an ingredient in red wine thought to improve insulin sensitivity, reduce risk of heart disease and increase longevity, does not appear to have those benefits in healthy women, according to new research from Washington University School of Medicine in St. Louis.