Genetic errors identified in 12 major cancer types

By analyzing the DNA in more than 3,000 tumors, scientists led by Li Ding, PhD, at The Genome Institute have identified 127 repeatedly mutated genes that likely drive the growth of a range of cancers in the body. The discovery sets the stage for devising new diagnostic tools and more personalized cancer treatments.

Scientists unravel mechanisms in chronic itching

New research at the School of Medicine shows that chronic itching, which can occur in many medical conditions, is different from the urge to scratch a mosquito bite. Chronic itching appears to incorporate more than just the nerve cells that normally transmit itch signals. In the image shown, researchers identified elevated signaling (in red) in nerve cells involved in both itch and in pain.

Stomach cells naturally revert to stem cells

Scientists from the School of Medicine and in the Netherlands have found that a class of specialized cells in the stomach reverts to stem cells more often than researchers had thought. One or more chief cells, which normally make digestive juices in the stomach, have changed into a stem cell in the image shown.

Public health conference ​​​to address obesity

The obesity epidemic and how science may be able to impact it is the focus of the upcoming annual conference of the Institute for Public Health at Washington University in St. Louis. Graham Colditz, MD, DrPH, deputy director of the Institute for Public Health and a disease prevention expert at Siteman Cancer Center, will deliver the keynote address.
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