Medicine & Health

In cells lining the airway, high levels of certain proteins have long been linked with the overproduction of mucus characteristic of diseases like asthma and COPD. New research from the School of Medicine provides clues to potentially counteract inappropriate mucus production.

Nancy Morrow-Howell, PhD, is a national leader in gerontology, widely known for her work on productive and civic engagement of older adults. She is also the Bettie Bofinger Brown Distinguished Professor of Social Policy at the Brown School, faculty director of productive aging research at the  Center for Social Development and director of the Harvey A. Friedman Center for Aging, part of the Institute for Public Health, all at Washington University in St. Louis.

James M. DuBois, DSc, PhD, has been named the Steven J. Bander Professor of Medical Ethics and Professionalism at the School of Medicine. In his research, DuBois develops measures to assess outcomes of training programs in ethics and professionalism in medicine and conducts social science studies of patient and research participant attitudes.

Scientists are eager to make use of stem cells’ extraordinary power to transform into nearly any kind of cell, but that ability also is cause for concern in cancer treatment. New research at the School of Medicine has revealed that these stem cells are present even in slow-growing, less aggressive tumors.

A reformulation of OxyContin (left) that makes it less likely to be abused than the older formulation (right) has curtailed the drug’s illicit use. But researchers at the School of Medicine have found that a significant percentage still abuse the drug despite package labeling that emphasizes its abuse-deterrent properties. 

Washington University School of Medicine and BJC HealthCare are planning to build a 12-to-14-story office building on the site of the Storz Building on the Medical Campus.

Researchers led by Samuel Achilefu, PhD, at the School of Medicine have devised a way to apply light-based therapy to deep tissues never before accessible. Instead of shining an outside light, they delivered light directly to tumor cells, along with a photosensitive source of free radicals that can be activated by the light to destroy cancer.

Stroke can lead to a wide range of problems such as depression and difficulty moving, speaking and paying attention. A new study led by Maurizio Corbetta, MD, at the School of Medicine has found evidence that stroke damage to “cables” buried inside the brain plays an important role in these impairments.

Evaluating military personnel with blast-related mild traumatic brain injuries, researchers have found that early symptoms of post-traumatic stress, such as anxiety, emotional numbness, flashbacks and irritability, are the strongest predictors of later disability. The study was led by the School of Medicine.

The stigma surrounding people with severe mental illness in India leads to increased poverty among them, especially women, according to new research led by Jean-Francois Trani, PhD, assistant professor at the Brown School at Washington University in St. Louis.