Medicine & Health

Washington University School of Medicine and St. Louis Children’s Hospital have opened a new pediatric medical center — the St. Louis Children’s Specialty Care Center — at Interstate 64/Highway 40 and Mason Road in west St. Louis County. The center welcomed its first patients June 2.

Victoria J. Fraser, MD, head of the Department of Medicine, was a featured speaker at TEDxStLouisWomen, Thursday, May 28. The presentations were part of TEDWomen, a national conference focused on women and girls as creators and change-makers. Fraser spoke about antibiotic resistance and its evolution into a public health crisis.

Munish C. Gupta, MD, has been appointed professor and chief of spine surgery in the Department of Orthopaedic Surgery at Washington University School of Medicine in St. Louis. He comes from the University of California, Davis and will assume his new duties Sept. 1.

Researchers have designed a nanoparticle-based therapy that is effective in treating mice with multiple myeloma, a cancer of bone marrow immune cells. Targeted specifically to the malignant cells, these nanoparticles protect their therapeutic cargo from degradation in the bloodstream and greatly enhance drug delivery into the cancer cells.

Studying West Nile virus infection in mice, scientists at Washington University School of Medicine in St. Louis have shown that an antiviral compound tightens the blood-brain barrier, making it harder for the virus to invade the brain.

A diabetes drug may have benefits beyond lower blood sugar in patients with HIV. New research from the laboratory of Kevin E. Yarasheski, PhD, suggests the drug may prevent cardiovascular problems because it works to reduce inflammation that is linked to heart disease and stroke in these patients. The drug both improved metabolism and reduced inflammation in HIV-positive adults on antiretroviral therapy.

​To the nearly 2 million people in the United States living with the loss of a limb, prosthetic devices provide restored mobility, yet lack sensory feedback. A team of engineers and researchers at Washington University is working to change that so those with upper limb prosthetics can feel hot and cold and the sense of touch through their prosthetic hands.

A newly discovered link between bacteria and immune cells sheds light on inflammatory bowel disease, an autoimmune condition that affects 1.6 million people in the United States, according to researchers at Washington University School of Medicine in St. Louis.

Researchers led by John F. DiPersio, MD, PhD, at the School of Medicine have designed a way to mitigate graft-versus-host disease, a common and often life-threatening complication of bone marrow transplants that are used to treat leukemia and other blood cancers. The method also employs a molecular imaging tool to help doctors identify patients most likely to develop this dangerous condition.

The Washington University AIDS Clinical Trials Unit is the first in the nation to open a clinical trial evaluating whether statins reduce heart attacks and strokes in patients with human immunodeficiency virus (HIV).