Potential treatment target identified for rare form of diabetes

Scientists working to find treatments for a severe form of diabetes called Wolfram syndrome have identified a gatekeeper in cells that prevents harmful molecules from spilling into places where they don’t belong and triggering cell death. The researchers, at Washington University School of Medicine, also found that the gatekeeper may be a good treatment target for other disorders caused by cellular stress.

Obesity, excess weight in U.S. continue upswing

Obesity and excess weight, and their negative impact on health, have become a significant focus for health-care experts in recent years. But new research at Washington University School of Medicine shows that an escalation in the number of those considered obese or overweight in the U.S. continues, signaling an ongoing upward swing in chronic health conditions as well.

WashU Expert: Supreme Court likely to uphold Obamacare tax credits, avoid chaos​

As the U.S. Supreme Court prepares to announce its decision in a lawsuit that threatens federal health insurance subsidies for more than 6 million Americans, health care economist Timothy D. McBride, PhD, professor in the Brown School at Washington University in St. Louis, is confident the high court will side with the Obama administration. If the court decides otherwise, low-income residents in many states will have little access to affordable healthcare, he warns.

Eye’s motion detection sensors identified

Studying mice, scientists at Washington University School of Medicine in St. Louis have identified a neural circuit in the retina that carries signals enabling the eye to detect movement. The finding could help in efforts to build artificial retinas for people who have suffered vision loss.

New clues in mice link cholesterol to fertility

Whether made by the body or ingested through diet, cholesterol plays a vital role in cells. Cholesterol also is a building block of steroids and hormones, including those that trigger puberty and support pregnancy. A new study, led by Daniel Ory, MD, implicates a surprising regulator of cholesterol in cells’ ability to make these hormones, especially in tissues associated with fertility, such as the ovaries.

Brown School study analyzes Twitter hashtags associated with diabetes

An analysis of Twitter hashtag use on the subject of diabetes provides new insights about spreading health information through social media. The study, led by Jenine Harris, PhD, assistant professor at the Brown School at Washington University in St. Louis, looked at the hashtag #diabetes and its interaction with two Twitter measures of engagement, retweeting and favoriting. The study found retweeting and favoriting was significantly lower for tweets about the number or percentage of people with diabetes, while favoriting was higher for tweets about health problems associated with diabetes.

New chief of pediatric orthopaedic surgery named

Charles A. Goldfarb, MD, has been appointed chief of pediatric orthopaedic surgery at Washington University School of Medicine and St. Louis Children’s Hospital. A hand and wrist specialist, Goldfarb currently is a professor of orthopaedic surgery, co-chief of the department’s hand and wrist service and medical director of the Washington University and Barnes-Jewish Orthopedic Center in Chesterfield.
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