Medicine & Health

Researchers at Washington University School of Medicine​ in St. Louis have identified “broadly neutralizing” antibodies that protect against infection by multiple, distantly related alphaviruses – including Chikungunya virus – that cause fever and debilitating joint pain. The discovery, in mice, lays the groundwork for a single vaccine or antibody-based treatment against many different alphaviruses.

High-dose vitamin D relieves joint and muscle pain for many breast cancer patients taking estrogen-lowering drugs, according to a new study from Washington University School of Medicine in St. Louis.

Emil R. Unanue, MD, an internationally renowned immunologist at the School of Medicine, has received a Sanofi-Institut Pasteur Award for his invaluable contributions to the field of immunology. The annual awards honor scientists who have made outstanding contributions to biomedical research in fields that profoundly affect global health.

Researchers at the School of Medicine have been awarded $13.7 million from the National Cancer Institute (NCI) to create new therapies for multiple myeloma, a cancer of the immune system.​ Led by Samuel Achilefu, PhD, (pictured) and Gregory Lanza, MD, PhD, at the newly created Center for Multiple Myeloma Nanotherapy, scientists will work to develop nanomaterials and drugs to treat the disease.

With the aim of producing high-quality X-rays with minimal radiation exposure, researchers at the School of Medicine have developed a new approach to imaging patients. Using proprietary software developed for the Microsoft Kinect system, the team has adapted hands-free technology used for the popular Xbox system to aid radiographers when taking X-rays.

To further the goal of improving patient safety and quality in health care, three institutions — the Goldfarb School of Nursing at Barnes-Jewish College, St. Louis College of Pharmacy and Washington University School of Medicine — have created the Center for Interprofessional Education (CIPE) at Washington University Medical Center.

A new study shows that the number of infant deaths and injuries attributed to crib bumpers has spiked significantly in recent years, prompting the researchers to call for a nationwide ban on the bedding accessory. The findings indicate that in the majority of incidents studied, crib bumpers were the sole cause of harm, rebutting beliefs that other items also in the cribs caused the deaths and injuries.

Researchers at the School of Medicine have received a five-year, $6.5 million grant to study the physiological underpinnings of developmental disabilities in children and to use the findings to search for novel ways to improve such children’s lives. The grant renews funding for the university’s Intellectual and Developmental Disabilities Research Center (IDDRC), which is directed by John N. Constantino, MD (left) and Bradley L. Schlaggar, MD, PhD.

​A personalized method for testing the effectiveness of drugs that treat multiple myeloma may predict quickly and more accurately the best treatments for individual patients with the bone marrow cancer. The process, developed by scientists at Washington University School of Medicine​ in St. Louis, also may aid patients with leukemia or lymphoma.

In trauma patients experiencing severe bleeding, researchers at Washington University School of Medicine in St. Louis will evaluate a drug already approved to minimize blood loss in people suffering from hemophilia — a genetic clotting disorder — or heavy menstrual periods.