Medicine & Health

Using MRIs, researchers at the School of Medicine have identified areas in the brains of children with Tourette’s syndrome that appear markedly different from the same areas in the brains of children who don’t have the neuropsychiatric disorder. The findings were published online Oct. 25 in the journal Molecular Psychiatry.

Scientists at Washington University School of Medicine in St. Louis and Stanford University report that they have designed small compounds that have the potential to correct the mitochondrial dysfunction that leads to Charcot-Marie-Tooth and other conditions involving mitochondria.

Scientists have linked mutations in a single gene to autism in people who have a rare tumor syndrome typically diagnosed in childhood. The findings, in patients with neurofibromatosis type 1 (NF1), may lead to a better understanding of the genetic roots of autism in the wider population.

As part of the White House BRAIN Initiative, researchers at Washington University School of Medicine in St. Louis have received two grants to develop tools to map and activate pathways in the brain using light.

Washington University School of Medicine in St. Louis has received a two-year, $8 million grant from the Bill & Melinda Gates Foundation to evaluate an investigational treatment regimen for lymphatic filariasis, a neglected tropical disease.

Dieters sometimes consume extra protein to stave off hunger and prevent loss of muscle tissue that often comes with weight loss. But a School of Medicine study found that eating too much protein eliminates an important health benefit of weight loss: improvement in insulin sensitivity, which is critical to lowering diabetes risk.

Research from the School of Medicine shows that surgery to correct nerve-compression shoulder injury can help Major League Baseball pitchers return to the game and perform at, or better than, pre-injury play.

Many children with sickle cell disease experience frequent and severe pain episodes, requiring emergency room visits or hospitalization. In search of more effective ways to treat such pain, researchers at Washington University School of Medicine in St. Louis have found that adding a low dose of the drug methadone to standard treatment can limit pain experienced by children with the condition.

Four research teams at Washington University School of Medicine in St. Louis have been collectively awarded nearly $2 million for research aimed at combating the growing threat of antibiotic resistance.

Jeffrey I. Gordon, MD, of Washington University School of Medicine in St. Louis, has been honored with the Steven C. Beering Award for his seminal contributions to establishing the field of human microbiome research. His research has revealed a vital relationship between the tens of trillions of microbes that live in the human gut and a person’s health status.