Gene linked to metabolism drives deadly brain cancer

Gene linked to metabolism drives deadly brain cancer

While a particular metabolic pathway shows potential to slow down the aging process, new research indicates a downside: That same pathway may drive brain cancer. The pathway, known as the nicotinamide adenine dinucleotide (NAD+) pathway, is overactive in a deadly form of brain cancer known as glioblastoma, according to a study by researchers at Washington University School of Medicine in St. Louis.
WashU Expert: Cures Act’s controversy continues

WashU Expert: Cures Act’s controversy continues

The 21st Century Cures Act, the vast bill aimed at bolstering medical research and revamping the way drugs are approved, is a step in the right direction but is far from perfect, says an expert on the health care industry at the School of Law at Washington University in St. Louis.
New research findings on most lethal type of leukemia

New research findings on most lethal type of leukemia

Patients with the most lethal form of acute myeloid leukemia (AML) – based on genetic profiles of their cancers – typically survive for only four to six months after diagnosis, even with aggressive chemotherapy. But new research led by the School of Medicine indicates that such patients, paradoxically, may live longer if they receive a milder chemotherapy drug.
New topical immunotherapy effective against early skin cancer

New topical immunotherapy effective against early skin cancer

A combination of two topical drugs that have been in use for years triggers a robust immune response against precancerous skin lesions, according to a new study. The research, from the School of Medicine and Harvard Medical School, shows that the therapy activates the immune system’s T cells, which then attack the abnormal skin cells. The study was published Nov. 21 in The Journal of Clinical Investigation.
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