Higher doses of radiation don’t improve survival in prostate cancer
A new study shows that higher doses of radiation do not improve survival for many patients with prostate cancer, compared with the standard radiation treatment. The analysis, which included 104 radiation therapy oncology groups across North America, was led by researchers at the School of Medicine.
Proposed Medicaid work requirements would affect fewer in Missouri
Proposed rules surrounding Medicaid recipients would affect a far smaller proportion of Missouri’s population than other states with similar legislation, according to research from the Center for Health Economics and Policy at Washington University in St. Louis.
3-D mapping babies’ brains
Research from a collaborative team at Washington University in St. Louis tested a 3-D method that could lead to new diagnostic tools that will precisely measure the third-trimester growth and folding patterns of a baby’s brain. Their findings might help to sound an early alarm on developmental disorders in preemies that could affect them later in life.
No progress seen in reducing antibiotics among outpatients
Despite public health campaigns aimed at reducing unnecessary prescriptions for antibiotics, the drugs continue to be prescribed at startlingly high rates in outpatient settings such as clinics and physician offices, according to a new School of Medicine study.
Gut microbes influence severity of intestinal parasitic infections
A new School of Medicine study indicates that gut microbes influence the severity of parasitic worm infections in developing countries. The findings suggest that manipulating the gut’s microbial communities may offer protection.
New way to fight sepsis: Rev up patients’ immune systems
A small clinical trial led by Richard S. Hotchkiss, MD, at the School of Medicine, shows that a drug that revs up the immune system holds promise in treating sepsis. The approach goes against the grain of earlier strategies that have relied on antibiotics and inflammatory medications to tamp down the immune system.
Decoy molecules target E. coli to treat UTIs in mice
School of Medicine researchers report they found a way to treat urinary tract infections without using antibiotics, at least in mice. The scientists are working on an alternative that would prevent bacteria from causing disease.
Uncertainty leads to treatment delays for young people with mental illness
Stigmas, attitudes of self-reliance and misattributing symptoms led a group of young adults experiencing their first episode of psychosis to delay seeking treatment, finds a new study from the Brown School at Washington University in St. Louis.
CRISPR enhances cancer immunotherapy
Scientists at the School of Medicine have used the gene-editing technology CRISPR to engineer human T cells that can attack human T cell cancers without succumbing to friendly fire. The study evaluating the approach in mice appears online in the journal Leukemia.
$6.8 million to fund research into Cantu syndrome, cardiovascular disease
Colin Nichols, the Carl F. Cori Professor of Cell Biology and Physiology, has received a grant to study how the genetic mutations underlying Cantu syndrome are linked to cardiovascular disease.
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