Medicine & Health

Pain researchers at the School of Medicine have shown in rodents that they can block receptors on brain cells that are responsible for the negative emotions associated with pain, such as sadness, depression and lethargy. The findings could lead to new, less addictive approaches to pain treatment.

School of Medicine researchers received $10.5 million from the Department of the Army to investigate whether an anti-seizure drug can prevent noise-induced hearing loss when given hours before exposure.

The movement to abolish clock-time changes each spring and fall is growing — and so is the scientific evidence. Experts say perennial standard time, or “wintertime,” is the best and safest option for public health.

Researchers at the School of Medicine have found a compound that may treat inflammatory bowel disease without directly targeting inflammation. The compound tamps down the activity of a gene linked to blood clotting.

When very young children talk about wanting to commit suicide, conventional wisdom is that they don’t understand what they’re saying. But School of Medicine research has found that depressed children ages 4 to 6 who think and talk about committing suicide understand what it means to die better than other kids of the same age. They also are more likely to think of death as something caused by violence.

With the aid of a grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, School of Medicine researchers are studying why immunity elicited by the flu vaccine wanes so rapidly. The goal is a better, longer-lasting flu vaccine.

A pair of events in Hong Kong and Mumbai helped to further strengthen Washington University’s impact in the Asia-Pacific region and showcase its world-leading, collaborative research.

Tobacco control experts at Washington University in St. Louis would welcome a crackdown on e-cigarette commercials on television and radio. But advertising restrictions, as recently suggested by a member of the Federal Communications Commission, are just one way to curb the vaping epidemic among America’s youth, said Doug Luke, professor at the Brown School and director of the Center for Public Health Systems Science.

Greg Bowman, at the Washington University School of Medicine, is leading one of the largest crowd-sourced computational biology projects in the world. Called Folding@home, it’s aimed at understanding how proteins fold into their proper shapes. Bowman understands the importance of protein folding more than most. He became legally blind by age 9 due to a condition caused when a protein doesn’t fold properly.

Over-testing for urinary tract infections (UTIs) leads to unnecessary antibiotic use, which spreads antibiotic resistance. Infectious disease specialists at the School of Medicine made changes to hospital procedures that cut urine tests by nearly half without compromising doctors’ abilities to detect UTIs.