Medicine & Health

Researchers at the School of Medicine have found a compound that may treat inflammatory bowel disease without directly targeting inflammation. The compound tamps down the activity of a gene linked to blood clotting.

When very young children talk about wanting to commit suicide, conventional wisdom is that they don’t understand what they’re saying. But School of Medicine research has found that depressed children ages 4 to 6 who think and talk about committing suicide understand what it means to die better than other kids of the same age. They also are more likely to think of death as something caused by violence.

With the aid of a grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health, School of Medicine researchers are studying why immunity elicited by the flu vaccine wanes so rapidly. The goal is a better, longer-lasting flu vaccine.

A pair of events in Hong Kong and Mumbai helped to further strengthen Washington University’s impact in the Asia-Pacific region and showcase its world-leading, collaborative research.

Tobacco control experts at Washington University in St. Louis would welcome a crackdown on e-cigarette commercials on television and radio. But advertising restrictions, as recently suggested by a member of the Federal Communications Commission, are just one way to curb the vaping epidemic among America’s youth, said Doug Luke, professor at the Brown School and director of the Center for Public Health Systems Science.

Greg Bowman, at the Washington University School of Medicine, is leading one of the largest crowd-sourced computational biology projects in the world. Called Folding@home, it’s aimed at understanding how proteins fold into their proper shapes. Bowman understands the importance of protein folding more than most. He became legally blind by age 9 due to a condition caused when a protein doesn’t fold properly.

Over-testing for urinary tract infections (UTIs) leads to unnecessary antibiotic use, which spreads antibiotic resistance. Infectious disease specialists at the School of Medicine made changes to hospital procedures that cut urine tests by nearly half without compromising doctors’ abilities to detect UTIs.

The School of Medicine has received a $15 million commitment from longtime benefactors Philip and Sima Needleman to support two cutting-edge research centers aimed at developing new treatments for diseases that collectively affect millions.

A School of Medicine study of adults with lumbar scoliosis and found that the most important factor in determining whether to do surgery is the extent of a patient’s disability due to his or her spinal deformity, as well as how much that disability interferes with day-to-day life.

School of Medicine surgeon Amy Moore, MD, has performed nerve transfer surgeries on children stricken with a rare paralyzing illness called acute flaccid myelitis. Researchers believe the condition may be caused by a common enterovirus.