The End of the Beginning
Cancer, Immunity and the Future of a Cure
A fascinating history of our understanding and the treatment of cancer by one of the leading figures in the field—who is also a pioneer on the cusp of a breakthrough.
‘Jumping genes’ drive many cancers
Mistakes in DNA are known to drive cancer growth. But a new study, from Washington University School of Medicine in St. Louis, heavily implicates a genetic phenomenon commonly known as “jumping genes” in the growth of tumors.
WashU Expert: What happens if ACA is eliminated?
The Trump administration said this week that the whole Affordable Care Act should be struck down in the courts. Doing so would have profound implications on health care and the economy, says an expert on health economics at Washington University in St. Louis.
Cannabis during pregnancy bumps psychosis risk in offspring
Pregnant women who use cannabis may slightly increase the risk their unborn child will develop psychosis later in life, suggests new research from Washington University in St. Louis.
Rineys give $15 million to develop, test therapies for neurodegenerative diseases
The School of Medicine has received a $15 million gift from Paula and Rodger Riney aimed at accelerating research and developing new treatments for two major neurodegenerative diseases: Alzheimer’s disease and Parkinson’s disease.
Probiotic bacteria evolve inside mice’s GI tracts
Probiotics – living bacteria taken to promote digestive health – evolve once inside the body and have the potential to become less effective and sometimes even harmful, according to a new study from the School of Medicine. The findings suggest that developers of probiotic-based therapeutics must consider how the probiotics might change after administration.
Home-based lifestyle intervention minimizes maternal weight gain
Weight gain during pregnancy and postpartum are important causes of long-term weight gain and the development of obesity-related diseases among women. A new study from Washington University in St. Louis finds providing a home-based lifestyle intervention effectively minimizes excess maternal weight gain during pregnancy and through 12-months postpartum in underserved African American women with obesity.
Medications to treat opioid addiction are effective, though not widely used
Although medications to treat opioid use disorder are safe and effective, most people who could benefit from these treatments do not receive them, finds a new report from the National Academies of Sciences, Engineering, and Medicine. The Brown School’s David Patterson Silver Wolf was one of the authors of the report.
Obese mouse mothers trigger heart problems in offspring
Mitochondria manufacture energy in every cell of the body, including heart muscle cells. A new study from the School of Medicine shows that cardiac mitochondria are abnormal in the offspring of mouse mothers that become obese due to a high-fat, high sugar diet. Those offspring then pass on the mitochondrial defects at least two more generations.
Student Gorham excels in the lab, on the track
Personal experience told Lisa Gorham, captain of the Washington University in St. Louis cross-country, track and indoor track teams, that team sports and adolescent mental health are linked. But what would the data say? Gorham has just published her findings in a leading journal — a rare accomplishment for an undergraduate researcher.
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