The End of the Beginning

The End of the Beginning

Cancer, Immunity and the Future of a Cure

A fascinating history of our understanding and the treatment of cancer by one of the leading figures in the field—who is also a pioneer on the cusp of a breakthrough.
WashU Expert: What happens if ACA is eliminated?

WashU Expert: What happens if ACA is eliminated?

The Trump administration said this week that the whole Affordable Care Act should be struck down in the courts. Doing so would have profound implications on health care and the economy, says an expert on health economics at Washington University in St. Louis.
Probiotic bacteria evolve inside mice’s GI tracts

Probiotic bacteria evolve inside mice’s GI tracts

Probiotics – living bacteria taken to promote digestive health – evolve once inside the body and have the potential to become less effective and sometimes even harmful, according to a new study from the School of Medicine. The findings suggest that developers of probiotic-based therapeutics must consider how the probiotics might change after administration.
Home-based lifestyle intervention minimizes maternal weight gain

Home-based lifestyle intervention minimizes maternal weight gain

Weight gain during pregnancy and postpartum are important causes of long-term weight gain and the development of obesity-related diseases among women. A new study from Washington University in St. Louis finds providing a home-based lifestyle intervention effectively minimizes excess maternal weight gain during pregnancy and through 12-months postpartum in underserved African American women with obesity.
Obese mouse mothers trigger heart problems in offspring

Obese mouse mothers trigger heart problems in offspring

Mitochondria manufacture energy in every cell of the body, including heart muscle cells. A new study from the School of Medicine shows that cardiac mitochondria are abnormal in the offspring of mouse mothers that become obese due to a high-fat, high sugar diet. Those offspring then pass on the mitochondrial defects at least two more generations.
Student Gorham excels in the lab, on the track

Student Gorham excels in the lab, on the track

Personal experience told Lisa Gorham, captain of the Washington University in St. Louis cross-country, track and indoor track teams, that team sports and adolescent mental health are linked. But what would the data say? Gorham has just published her findings in a leading journal — a rare accomplishment for an undergraduate researcher.
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