Key collaborators

Key collaborators

Jeff Gordon’s influence in the race to understand the human gut microbiome extends to the many students he has mentored at the Washington University School of Medicine. Here is a small sampling of his former students and postdocs, and where they are now.

Vitamin D prevents clogged arteries in diabetics

People with diabetes often develop clogged arteries that cause heart disease. New research at Washington University School of Medicine in St. Louis has found that when vitamin D levels are adequate in people with diabetes, blood vessels are less likely to clog. But in patients with insufficient vitamin D, immune cells bind to blood vessels near the heart, then trap cholesterol to block those blood vessels.

The biology behind alcohol-induced blackouts

Neuroscientists at Washington University School of Medicine in St. Louis have identified the brain cells involved in alcohol-related blackouts and the molecular mechanism that appears to underlie them. Alcohol interferes with key receptors in the brain, which in turn manufacture steroids that inhibit long-term potentiation, a process that strengthens the connections between neurons and is crucial to learning and memory. 

Restricting calories lowers body temperature, may predict longer lifespan

Nutrition and longevity researchers, including Luigi Fontana, MD, PhD, have found more evidence that eating less may help people live longer. They report that individuals who significantly reduce their calorie intake have lower core body temperatures. Mice and rats consuming fewer calories also have lower core body temperatures, and they live significantly longer than littermates eating a standard diet. 

Could soy reduce asthma symptoms?

In a recent clinical study of people with asthma, scientists found that those who consumed the least amount of soy had the most flare-ups of their asthma symptoms. Washington University School of Medicine in St. Louis and other institutions around the country are conducting a trial to test the effect of soy compounds on asthma symptoms.
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