Anti-aging compound that improves metabolic health in mice improves muscle glucose metabolism in people
In the first clinical trial of nicotinamide mononucleotide (NMN), School of Medicine researchers have found that the compound previously demonstrated to counteract aspects of aging and improve metabolic health in mice also has clinically relevant effects in people.
Gordon receives Kober Medal
Jeffrey Gordon, MD, has received the 2021 Kober Medal, one of the highest awards in academic medicine. Given by the Association of American Physicians, the honor recognizes Gordon’s extraordinary contributions to the field of gut microbiome research.
For malnourished children, a new type of microbiome-directed food boosts growth
A new study shows that a therapeutic food designed to repair the gut microbiomes of malnourished children is better than standard therapy in supporting their growth. The study was led by researchers at the School of Medicine and was published in The New England Journal of Medicine.
Charles J. Kilo, professor of clinical medicine, 94
Charles J. Kilo, MD, a former professor of clinical medicine at the School of Medicine, died of pneumonia March 15 in Naples, Fla. He was 94. Kilo and collaborators at the School of Medicine were among the first to demonstrate that diabetes complications are linked to the duration of the disease and the degree of blood sugar control.
An receives grant to study egg consumption
Ruopeng An, assistant professor at the Brown School, has received a $90,000 three-year grant from the Egg Nutrition Center for a project titled “Influence of Whole Egg Consumption on Diet Quality and Cognitive Function among U.S. Older Adults.”
State laws can bolster physical education among children, study finds
The presence and strength of state physical education (P.E.) laws positively affected P.E. attendance and the frequency and duration of physical activity throughout the day, suggests a new analysis from the Brown School.
Scientists find genetic link to clogged arteries
A new study from the School of Medicine has identified a gene — called SVEP1 — that makes a protein that influences the risk of coronary artery disease independent of cholesterol.
Foodborne fungus impairs intestinal wound healing in Crohn’s disease
A foodborne fungus that is harmless to most people exacerbates gastrointestinal symptoms in people with Crohn’s disease by preventing intestinal ulcers from healing, according to a new study from the School of Medicine and the Cleveland Clinic.
Toxin provides clues to long-term effects of diarrhea caused by E. coli
A study from researchers at Washington University School of Medicine in St. Louis has found that a toxin produced by E. coli changes intestinal cells to benefit itself, an ability that could provide a clue to why the bacteria have been linked to nutritional problems such as malnutrition and stunted growth.
Uncovering genetic roots of marijuana use disorder
An international team of researchers led by scientists at the School of Medicine has identified two regions in our DNA — one newly identified and a second that replicates a past finding — that appear to contribute to one’s risk of becoming dependent on marijuana.
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