Dormant viruses re-emerge in patients with lingering sepsis, signaling immune suppression
A provocative study links prolonged episodes of sepsis — a life-threatening infection and leading cause of death in hospitals — to the reactivation of otherwise dormant viruses in the body. Pictured is the Epstein-Barr virus.
Imbalanced hearing is more than a mild disability
Asymmetric hearing is a difference between the two ears’ ability to detect and process sound. New studies indicate that people with asymmetric hearing experience greater communication difficulties than previously assumed. Researchers led by Jill B. Firszt, PhD, have received a $3 million grant from the National Institutes of Health (NIH) to study the effects of asymmetric hearing loss in adults and children.
Washington People: Anthony Odibo, MD
Anthony Odibo, MD, specializes in identifying and treating high-risk pregnancies using ultrasound and genetic testing. In his research, he evaluates the effectiveness of fetal surgeries and diagnostic techniques before birth.
Splints favored for kids’ forearm buckle fractures
When children fall and try to catch themselves with an outstretched hand, they can suffer “buckle fractures,” forearm injuries traditionally treated with casts. But new research shows that removable splints are cpreferred by patients and parents, building on earlier findings that such splints are just as effective as casts. Shown are study co-authors Kristine G. Williams, MD, holding a splint, and Janet D. Luhmann, MD.
Nanoparticles loaded with bee venom kill HIV
Nanoparticles carrying a toxin found in bee venom can destroy human immunodeficiency virus (HIV) while leaving surrounding cells unharmed, researchers at the School of Medicine have shown. The finding is an important step toward developing a vaginal gel that may prevent the spread of HIV. Shown are nanoparticles (purple) carrying melittin (green) that fuse with HIV (small circles with spiked outer ring), destroying the virus’s protective envelope.
Researchers block morphine’s itchy side effect
Itching is one of the most prevalent side effects of powerful, pain-killing drugs like morphine, oxycodone and other opioids. For many years, scientists have scratched their own heads about why the drugs so often induce itch while they are suppressing pain. Now researchers at Washington University School of Medicine in St. Louis have shown they can control the opioid-induced itching without interfering with a drug’s ability to relieve pain.
Study looks at why second ACL surgeries often fail
Sports medicine specialists at Washington University School of Medicine in St. Louis, including Rick Wright, MD, and Corey Gill, MD, are leading a national study analyzing why a second surgery to reconstruct a tear in the knee’s anterior cruciate ligament (ACL) carries a high risk of bad outcomes. Between 1 percent to 8 percent of ACL repairs fail. Most patients then opt to have a second operation, but the failure rate for those subsequent surgeries is almost 14 percent.
Chromosomal abnormality found for inherited clubfoot
Although clubfoot is one of the most common congenital birth defects, few genetic causes have been found. Now, researchers at Washington University School of Medicine in St. Louis have found what they believe to be the most common cause of inherited clubfoot yet discovered.
Easily blocked signaling protein may help scientists stop parasites
Researchers at Washington University School of Medicine in St. Louis have identified a parasite protein that has all the makings of a microbial glass jaw: it’s essential, it’s vulnerable and humans have nothing like it, meaning scientists can take pharmacological swings at it with minimal fear of collateral damage.
High eye pressure: monitor or treat?
Most people at risk for developing glaucoma due to high eye pressure do not need treatment, according to a large, multi-center study.
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