Medicine & Health

​​Anthony Odibo, MD, specializes in identifying and treating high-risk pregnancies using ultrasound and genetic testing. In his research, he evaluates the effectiveness of fetal surgeries and diagnostic techniques before birth.​

When children fall and try to catch themselves with an outstretched hand, they can suffer “buckle fractures,” forearm injuries traditionally treated with casts. But new research shows that removable splints are cpreferred by patients and parents, building on earlier findings that such splints are just as effective as casts. Shown are study co-authors Kristine G. Williams, MD, holding a splint, and Janet D. Luhmann, MD.

Nanoparticles carrying a toxin found in bee venom can destroy human immunodeficiency virus (HIV) while leaving surrounding cells unharmed, researchers at the School of Medicine have shown. The finding is an important step toward developing a vaginal gel that may prevent the spread of HIV.  Shown are nanoparticles (purple) carrying melittin (green) that fuse with HIV (small circles with spiked outer ring), destroying the virus’s protective envelope.

Itching is one of the most prevalent side effects of powerful, pain-killing drugs like morphine, oxycodone and other opioids. For many years, scientists have scratched their own heads about why the drugs so often induce itch while they are suppressing pain. Now researchers at Washington University School of Medicine in St. Louis have shown they can control the opioid-induced itching without interfering with a drug’s ability to relieve pain.  

Sports medicine specialists at Washington University School of Medicine in St. Louis, including Rick Wright, MD, and Corey Gill, MD, are leading a national study analyzing why a second surgery to reconstruct a tear in the knee’s anterior cruciate ligament (ACL) carries a high risk of bad outcomes. Between 1 percent to 8 percent of ACL repairs fail. Most patients then opt to have a second operation, but the failure rate for those subsequent surgeries is almost 14 percent.

Although clubfoot is one of the most common congenital birth defects, few genetic causes have been found. Now, researchers at Washington University School of Medicine in St. Louis have found what they believe to be the most common cause of inherited clubfoot yet discovered.  

Researchers at Washington University School of Medicine in St. Louis have identified a parasite protein that has all the makings of a microbial glass jaw: it’s essential, it’s vulnerable and humans have nothing like it, meaning scientists can take pharmacological swings at it with minimal fear of collateral damage.

Most people at risk for developing glaucoma due to high eye pressure do not need treatment, according to a large, multi-center study.

Pig heart valves used to replace defective aortic valves in human patients failed much earlier and more often than expected, says a report from cardiac surgeons at the School of Medicine. This is the first report to demonstrate this potential problem, the researchers say.

Top: normal lungs. Bottom: asthmatic lungs.Many young children who get a severe skin rash develop asthma months or years later. Doctors call the progression from eczema, or atopic dermatitis, to breathing problems the atopic march. Now scientists at the School of Medicine have uncovered what might be the key to atopic march. They’ve shown that a substance secreted by damaged skin circulates through the body and triggers asthmatic symptoms in allergen-exposed laboratory mice.